Mechanics of column beds: II. Modeling of coupled stress‐strain‐flow behavior

Abstract

The rheological beha®ior of a bed of packing material during its consolidation was in®estigated using an elastic-plastic model, the Frictional Material Model. This model takes into account the beha®ior of the packing material under compression stress, its consolidation, its internal friction, its friction against the column wall, and the depen-

Shell particles, trials, tribulations and triumphs

“…Admittedly, however, the shape of the particles and the smoothness of their external surface may contribute to some extent to the resistance they opposes to the stream [33]. It seems probable that the influence of the nature of the particle surface (e.g., its smoothness) on the permeability is indirect and results more from the friction between the particles and between the bed and the internal surface of the column tube, because these frictions determine the external porosity of the packed bed and the packing density of the particles [34,35].…”

Advances in monolithic silica columns for high-performance liquid chromatography

“…However, at the same flow rate in 3.5 μm column provides a higher resistance system. One of the most important properties of porous beds in HPLC is the degree of radial homogeneity (Yew, Drumm, and Guiochon, 2003a;Yew, Ureta, Shalliker, Drumm, and Guiochon, 2003b). Mobile phase should percolate through the bed or it may cause a deleterious increase in bandwidth (Guiochon et al 1997).…”

Bioseparations

“…We note here that an important application is the testing of columns for packing non-uniformity (Lightfoot et al, 2003b), which can be a major practical problem Guiochon et al, 1997;Shalliker et al, 2002Yew et al, 2003).…”