Shell particles, trials, tribulations and triumphs

Guiochon, Georges; Gritti, Fabrice

doi:10.1016/j.chroma.2011.01.080

Cited by 294 publications

(208 citation statements)

References 110 publications

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“…Particles, which contain a tunable mesoporous shell on top of a solid, i.e., impermeable core (core-shell particles) also enable the independent control of the internal diffusion distance in fixed beds (shell thickness) and the interparticle macropore size (governed by the overall particle diameter), since the size of the solid core and the shell thickness are adjustable relative to another. In HPLC, recently developed core-shell particles (smaller than 3 mm) [25,34] indeed make the competition for monoliths very hard. In catalysis, it reflects the so-called egg-shell particles [41,47].…”

Section: Examples Of Monoliths In Separation and Catalysismentioning

confidence: 99%

Sol‐Gel and Porous Glass‐Based Silica Monoliths with Hierarchical Pore Structure for Solid‐Liquid Catalysis

Enke

Gläser

Tallarek

2016

Chemie Ingenieur Technik

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This work draws attention to both prospects and challenges for silica monoliths in solid-liquid catalysis at ultrahigh efficiency. The fundamental advantages of silica monoliths as support structure over particulate fixed beds and organicpolymer monoliths are illustrated as well as recent applications as flow-through microreactors for the production of fine chemicals. Preparation routes to sol-gel and porous glass-based silica monoliths featuring a hierarchical pore structure are described and their potential use as short-contact-time reactors is highlighted together with a view on the multiscale characterization and their rational design by establishing quantitative synthesis-morphology-transport relationships.

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Section: Examples Of Monoliths In Separation and Catalysismentioning

confidence: 99%

Sol‐Gel and Porous Glass‐Based Silica Monoliths with Hierarchical Pore Structure for Solid‐Liquid Catalysis

Enke

Gläser

Tallarek

2016

Chemie Ingenieur Technik

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“…On the other hand, compared to non-porous particles, they provide a larger surface area for separation which eliminates the need for using smaller particles for better separation at the cost of increased back-pressure [3]. The popularity of core-shell particles increased especially after Halo particles were introduced by Advanced Material Technologies in 2006 [4]. Core-Shell particles are typically produced by coating solid silica spheres layer after layer (hence referred to as the layer-by-layer approach) to create the porous shell around them.…”

Section: Introductionmentioning

confidence: 99%

“…Core-Shell particles are typically produced by coating solid silica spheres layer after layer (hence referred to as the layer-by-layer approach) to create the porous shell around them. This method affords a highly homogeneous pore size distribution and a smooth geometry [4].…”

Section: Introductionmentioning

confidence: 99%

Modelling of Diffusion in Random Packings of Core-Shell Particles

Hatipoğlu¹,

Koku²

2017

HJBC

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Ç ekirdek-Kabuk tipi parçacıklar kromatografide sıklıkla kullanılan malzemelerdir. Bu çalışmada, Çekirdek-Kabuk parçacıklarının etrafında gerçekleşen difüzyonu taklit etmeye yönelik bir matematik modeli geliştirilmiştir. Difüzyonun simulasyonu için rastgele-yürüyüş temelli bir algoritma oluşturulmuş ve basit geometrik yapılar ve bağıntılardan oluşan bir Çekirdek-Kabuk geometrisi hesaplanmıştır. Bu parçacıklardan oluşan rastgele-istiflenmiş bir yapı üzerinde difüzyon simülasyonları gerçekleştirilmiştir. Model sonuçlarından elde edilen zamana bağlı difüzyon katsayısının davranışı, nükleer manyetik rezonans deneyleri vasıtasıyla gözenekli ortamlarda bir maddenin zamana bağlı öz-difüzyon katsayısının ölçüldüğü daha önceki bir çalışmanın sonuçlarıyla uyumludur. Anahtar KelimelerÇekirdek-Kabuk, Difüzyon, Rastgele-Yürüyüş, Geometri. A B S T R A C TC ore-Shell particles are commonly used materials in chromatography. In this study, a mathematical model that mimics diffusion around Core-Shell particles was developed. A random-walk based algorithm was implemented to simulate diffusion and a Core-Shell particle geometry was computationally formed, based on simple geometric constructs and relations. Diffusion simulations were carried out on a randomly packed geometry formed from these particles. The behavior of time-dependent diffusivity data obtained from the model was found to be consistent with prior literature data from nuclear magnetic resonance experiments where transient diffusivity of a self-diffusing substance was measured in porous media.

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“…Several studies have been devoted to the mass transfer properties of coreeshell particles, and it could be demonstrated that the efficiency of these particles is considerably higher than that of fully porous particles of the same size (Daneyko et al, 2015;Deridder and Desmet, 2012;Fekete et al, 2009;Gritti and Guiochon, 2013c;Guiochon and Gritti, 2011;Lambert et al, 2014;Liekens et al, 2011). We have compared column performance for three fully porous (Zorbax C18) and two coreeshell (Poroshell 120 C18) columns, where each particle type is made by a similar manufacturing process in different particle sizes.…”

Section: Experimental Determination Of Hen Curves For Coreeshell and mentioning

confidence: 99%

“…In particular, coreeshell particles have become very successful and are now available in various particle sizes (between 1.3 and 5 mm) and chemistries (González-ruiz et al, 2015;Guiochon and Gritti, 2011;Hayes et al, 2014;Tanaka and McCalley, 2016). Certain coreeshell materials are also available with larger pore sizes for the separation of biomolecules Fekete et al, 2012aWagner et al, 2012).…”

Section: Introductionmentioning

confidence: 99%