Mechanical ventilation: invasive versus noninvasive

Brochard, Laurent

doi:10.1183/09031936.03.00050403

Cited by 106 publications

(82 citation statements)

References 91 publications

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“…The important role of noninvasive ventilation in managing episodes of respiratory failure is fully discussed elsewhere in the present supplement [35]. It has certainly improved care for many chronic obstructive pulmonary disease patients and allowed some to undergo therapy that might otherwise be denied them.…”

Section: Maintaining Gas Exchangementioning

confidence: 99%

Respiratory failure in chronic obstructive pulmonary disease

Calverley¹

2003

European Respiratory Journal

103

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Respiratory failure in chronic obstructive pulmonary disease. P.M.A. Calverley. #ERS Journals Ltd 2003. ABSTRACT: Respiratory failure is still an important complication of chronic obstructive pulmonary disease (COPD) and hospitalisation with an acute episode being a poor prognostic marker. However, other comorbid conditions, especially cardiovascular disease, are equally powerful predictors of mortality.The physiological basis of acute respiratory failure in COPD is now clear. Significant ventilation/perfusion mismatching with a relative increase in the physiological dead space leads to hypercapnia and hence acidosis. This is largely the result of a shift to a rapid shallow breathing pattern and a rise in the dead space/tidal volume ratio of each breath. This breathing pattern results from adaptive physiological responses which lessen the risk of respiratory muscle fatigue and minimise breathlessness.Treatment is directed at reducing the mechanical load applied to each breath, correcting specific precipitating factors, e.g. bacterial infection, and maintaining gas exchange. Both bronchodilators and oral corticosteroids can improve spirometric results in exacerbations of COPD and should be routinely offered to patients with respiratory failure. Controlled oxygen is still not always prescribed appropriately and high inspired oxygen concentrations can lead to severe acidosis by either worsening ventilation/perfusion mismatching and/or inducing a degree of hypoventilation. Ventilatory support using noninvasive ventilation has revolutionised the approach to these patients.Acute respiratory failure due to chronic obstructive pulmonary disease remains a common medical emergency that can be effectively managed. More attention should be focused on the prevention of these episodes and identifying the factors which cause early relapse. Eur Respir J 2003; 22: Suppl. 47, 26s-30s.

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Section: Maintaining Gas Exchangementioning

confidence: 99%

Respiratory failure in chronic obstructive pulmonary disease

Calverley¹

2003

European Respiratory Journal

103

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“…Non-invazif mekanik ventilasyon göğüs hastalıkları tarihine en büyük icatlardan biri olarak girmiş olup uygun vakalarda birçok entübasyonunun önüne geçmiş ve ekstübasyon sonrası dönemlerde de destek tedavisi olarak kullanılmaktadır [4]. İnvazif mekanik ventilasyondan farklı olarak NIMV'de maske desteği ile ventilasyon sağlanır.…”

Section: Discussionunclassified

A case of pneumothorax due to non-invasive mechanical ventilation

Koc

Dökme²,

Bayraktar³

et al. 2014

J Clin Exp Invest

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Emphysema is enlargement of alveolus, alveolary ducts and destruction of alveolary wall. One of complications of non-invasive mechanical ventilation (NIMV) is barotrauma of damaged lung. Here we present a 75 years old male who had Chronic Obstructive Pulmonary Disease (COPD), emphysema for 5 years and suffered from pneumothorax after NIMV. During treatment with NIMV his general condition deteriorated and oxygen saturation decreased immediately. Chest X-ray and tomography revealed pneumothorax. Chest tube inserted under local anesthesia. Although NIMV might seem like innocent, in patients whose general condition immediately worsens, oxygen saturation decreases, has emphysema and bullous lesions pneumothorax must be excluded. J Clin Exp Invest 2014; 5 (3): 469-471

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“…Noninvaziv mekanik ventilasyon (NIMV) yapılan çalışmalarda seçilmiş vakalarda VİP insidansını ve mortalitesini azalttığını gösteren bir yöntemdir (21). Endotrakeal entübasyonu önleyerek VİP oluşması için major bir risk faktörünü ortadan kaldırmaktadır.…”

Section: Mini Bronkoalveolar Lavaj (Bal)unclassified

Ventilatör İlişkili Pnömoni

Gündogdu¹,

Dikensoy²

2014

Toraks Cer Bult

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Ventilator-associated pneumonia (VAP) is defined as nosocomial pneumonia, which develops after 48 hours of mechanical ventilatory support in a patient who does not have pneumonia prior to intubation. VAP leads to prolonged mechanical ventilation, prolonged hospitalization, overuse of antibiotics, and increased medical costs. According to the National Nosocomial Infection Surveillance System (NNIS), one-third of all nosocomial infections in ICUs are pneumonia; of these, 83% is associated with mechanical ventilation. Care procedures should be performed in patients that have a high rısk for VAP to reduce risk factors, and early diagnosis should be provided. When VAP is diagnosed clinically, lower respiratory tract samples should be taken immediately, and empirical treatment should be started without waiting for culture results. Culture results and clinical response should be evaluated, and treatment should be reorganized in the first 48-72 hours.

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Mechanical ventilation: invasive versus noninvasive

Cited by 106 publications

References 91 publications

Respiratory failure in chronic obstructive pulmonary disease

Respiratory failure in chronic obstructive pulmonary disease

A case of pneumothorax due to non-invasive mechanical ventilation

Ventilatör İlişkili Pnömoni

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