Ventilator-associated pneumonia (VAP) is defined as nosocomial pneumonia, which develops after 48 hours of mechanical ventilatory support in a patient who does not have pneumonia prior to intubation. VAP leads to prolonged mechanical ventilation, prolonged hospitalization, overuse of antibiotics, and increased medical costs. According to the National Nosocomial Infection Surveillance System (NNIS), one-third of all nosocomial infections in ICUs are pneumonia; of these, 83% is associated with mechanical ventilation. Care procedures should be performed in patients that have a high rısk for VAP to reduce risk factors, and early diagnosis should be provided. When VAP is diagnosed clinically, lower respiratory tract samples should be taken immediately, and empirical treatment should be started without waiting for culture results. Culture results and clinical response should be evaluated, and treatment should be reorganized in the first 48-72 hours.
Objective: Bariatric surgeries increased in the last decades likewise obesity. The need for high doses of neuromuscular blocking agents in these surgeries may cause residual paralysis and also critical respiratory events and late complications such as hypoxemia, pneumonia, atelectasis, and the possibility of reintubation. The purpose of this study to evaluate the effect of sugammadex on respiratory parameters. Materials and method: 62 patients are included the study and they were assigned to one of the two groups randomly. LSG operation was performed on all the patients based on standard anesthesia management. In Group S (n=31), Sugammadex 2 mg/kg was administered for the reversal of rocuronium. In Group N (n=31), Neostigmine 0.05 mg/kg was administered together with atropine 0.02 mg/kg for the reversal of rocuronium. Extubation duration, Aldrete scores at 5, 10, and 15 minutes after extubation, PACU duration, FEV1 values of RFT, ABG values, mobilization time were analyzed. Results: In group S, patients have higher PO2 and lower PCO2 levels, shorter mobilization times, and an Aldrete score of 15 sooner, and moreover, they occupy the operating room and PACU to a lesser extent but FEV1 values did not differ between groups. Conclusion: In conclusion, sugammadex allows a safe and rapid recovery from deep rocuronium-induced neuromuscular blockade after LSG surgery.
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