2012
DOI: 10.1590/s0102-86502012000300009 View full text |Buy / Rent full text
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Abstract: PURPOSE:To determine biomechanical property of autogenous bone graft covered with hydroxyapatite in the defect of radial bone in rabbit. METHODS: Eighteen adult male New Zealand white rabbits were used which were divided into three groups (I, II, III) of six rabbits each. A segmental bone defect of 10 mm in length was created in the middle of the right radial shaft under general effective anesthesia in all rabbits and were stabilized using mini-plate with four screws. The defects In group I were left as such w… Show more

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“…, ,b) In view of this, the results in this study were enhanced through the creation of critical defects of 6‐mm diameter, which will not close spontaneously and therefore demonstrate the regenerative potential of the biomaterials under observation (Sharifi et al. ). No membranes were placed for an exclusive evaluation of the biological behavior of the biomaterial regarding critical defect.…”
Section: Discussionmentioning
“…Despite the New Zealand rabbit's rapid metabolic activity, other studies have established its validity as an experimental model for testing biomaterials used for bone replacement. (Calvo-Guirado et al 2014 In view of this, the results in this study were enhanced through the creation of critical defects of 6-mm diameter, which will not close spontaneously and therefore demonstrate the regenerative potential of the biomaterials under observation (Sharifi et al 2012). No membranes were placed for an exclusive evaluation of the biological behavior of the biomaterial regarding critical defect.…”
Section: R E T Rmentioning
“…In view of this, the results in this study were enhanced through the creation of critical defects of 6 mm diameter, which will not close spontaneously and therefore demonstrate the regenerative potential of the biomaterials under observation (Sharifi et al. ).…”
Section: Discussionmentioning
“…Despite the New Zealand rabbit's rapid metabolic activity, other studies have established its validity as an experimental model for testing biomaterials used for bone replacement (Calvo-Guirado et al 2012). In view of this, the results in this study were enhanced through the creation of critical defects of 6 mm diameter, which will not close spontaneously and therefore demonstrate the regenerative potential of the biomaterials under observation (Sharifi et al 2012).…”
Section: Discussionmentioning
“…A scaffold with this type of architecture can potentially provide the necessary porosity in the internal phase for tissue ingrowth with reduced porosity in the external phase to meet the immediate mechanical demands for the repair of large segmental bone defects . POC‐Click‐HA scaffolds were fabricated and characterized for their resulting geometries, mechanical properties, and efficacy to repair 10‐mm long segmental radial defects in rabbits …”
Section: Introductionmentioning