Mechanical optic neuropathy in high myopia

Bontzos, Georgios; Plainis, Sotiris; Papadaki, Efrosini; Giannakopoulou, Trisevgeni; Detorakis, Εfstathios T.

doi:10.1111/cxo.12548

Cited by 7 publications

(6 citation statements)

References 25 publications

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“…In these 3 examples of hyperopia, emmetropia and high myopia we could visualize how there was limited free space available in the congested myopic orbital cavity. This finding might have important implications for the anatomical and functional status of the optic nerve, as previously suggested [36].…”

Section: Discussionsupporting

confidence: 76%

Quantification of effective orbital volume and its association with axial length of the eye. A 3D-MRI study

Bontzos

Papadaki

Mazonakis

et al. 2019

rjo

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Objective: To measure the effective orbital volume (EOV) from magnetic resonance images, and investigate its relationship with axial length (AL) in those parameters. Methods: Cross-sectional, 3D-MRI study. 54 eyes of 54 patients (25 males) were included in this work. Patient weight, height and head circumference were also measured. Orbital and eyeball volumes were calculated after image segmentation. The difference between those values volume was assessed, estimating the EOV for each eye. Results: Mean eyeball volume was 7.83 ± 2.27 mm 3 , mean orbital volume 26.81 ± 0.59 mm 3 and EOV 21.64 ± 0.19 mm 3 . The orbital volume was significantly higher in the male group (Wilcoxon signed-rank tests Z=-1.51, p<0.001; Z=-3.57, p<0.001 respectively). EOV was significantly correlated with AL in both males (r=-0.71, p<0.001) and females (r=-0.73, p<0.001), whereas it was also significantly associated with patient height (r=0.261, p=0.03). Associations between EOV and other age, axial and anthropometric characteristics were not statistically significant. Conclusions: Findings of this study could be of valuable importance in various clinical situations in which quantification of orbital volume is needed, such as orbital decompression in Graves' orbitopathy, volume restoration in orbital fractures or other orbital reconstructive surgery. In surgical interventions, clinical relationships should be carefully taken under consideration to avoid iatrogenic injury.

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Section: Discussionsupporting

confidence: 76%

Quantification of effective orbital volume and its association with axial length of the eye. A 3D-MRI study

Bontzos

Papadaki

Mazonakis

et al. 2019

rjo

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“…It has been speculated that excessive elongation of the axial length could lead to mechanical damages in the retina and the optic nerve by stretching the wall of the eyeball [10]. As demonstrated in this study, retinoschisis, mCNV, chorioretinal atrophy, and optic neuropathy are more often observed in cases with posterior staphyloma.…”

Section: Discussionsupporting

confidence: 51%

Ultra-Widefield Retinal Imaging for Analyzing the Association Between Types of Pathological Myopia and Posterior Staphyloma

Mimura

Mori

Torii

et al. 2019

JCM

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High myopia may develop to pathologic myopia, which brings severe visual impairment; however, the etiology is not fully understood. We, therefore, investigated the relationship between the presence of posterior staphyloma and posterior ocular disorders by assessing the patients with high myopia. A retrospective study was performed for the patients, who have more than 26 mm of the axial length and of whom fundus photography was taken with an ultra-widefield retinal imaging system. The objectives were 138 cases encompassing 229 eyes. In 138 cases, 91 were bilateral and 47 were unilateral. The averages ± SD of axial length of bilateral and unilateral were 28.8 ± 2.2 mm, 27.3 ± 1.2 mm, respectively, showing statistically significant difference. The number of eyes with and without posterior staphyloma were 107 (46.7%) and 122 (53.3%), respectively. Retinal detachment and retinal breaks are more observed in cases without posterior staphyloma (p = 0.017). Myopic choroidal neovascularization (mCNV) (p = 0.002), chorioretinal atrophy (p < 0.001), retinoschisis (p < 0.001), and optic neuropathy (p = 0.038) are more often seen in cases with posterior staphyloma. In conclusion, the prevalence rates of myopic choroidal neovascularization, retinal choroidal atrophy, and optic neuropathy were significantly higher with posterior staphyloma. The rate of periocular disorders such as retinal detachment was significantly higher without posterior staphyloma. These results indicate associations between types of pathological myopia and presence or absence of posterior staphyloma analyzed by ultra-widefield retinal imaging.

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“…Thus, it is reasonable to hypothesize that a deformity of the eye by a staphyloma may result in mechanical damage. [14]…”

Section: Discussionmentioning

confidence: 99%

Estimation of morphological characteristics in asymmetrical myopic posterior staphyloma using optical coherence tomography

Bontzos

Papadaki

Maris

et al. 2018

Middle East Afr J Ophthalmol

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PURPOSE:Posterior staphyloma is an ocular complication associated with high myopia and reflects degenerative changes on the sclera. Its morphology is associated with chorioretinal atrophy and myopic maculopathy. The purpose of this study was to validate the efficacy of optical coherence tomography (OCT) in providing a simple estimation of the staphyloma pattern.MATERIALS AND METHODS:Observational case-series study of high myopic patients with posterior staphylomas. Patients were examined using the star scan pattern OCT in different radial planes. Three-dimensional (3D) magnetic resonance tomography was also performed to visualize the anatomical characteristics of the posterior pole. 3D-segmentation and curvature analysis were also performed.RESULTS:Eight patients were totally enrolled in this pilot study. Our study pool consisted of 2 wide macular staphylomas, 2 narrow macular staphylomas, and 4 barrel-shaped staphylomas. Our preliminary results revealed that patients displayed mirror-image distortion in the steeper staphyloma axis. In the barrel-shaped subtype, no image distortion was displayed in any plane.CONCLUSION:We estimated the axis of the smaller base curvature by noting the distortion pattern in the different radial axis. The recognition of pathologic axial myopia is important since there is a risk of permanent vision loss from vision to threatening sequelae.

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Mechanical optic neuropathy in high myopia

Cited by 7 publications

References 25 publications

Quantification of effective orbital volume and its association with axial length of the eye. A 3D-MRI study

Quantification of effective orbital volume and its association with axial length of the eye. A 3D-MRI study

Ultra-Widefield Retinal Imaging for Analyzing the Association Between Types of Pathological Myopia and Posterior Staphyloma

Estimation of morphological characteristics in asymmetrical myopic posterior staphyloma using optical coherence tomography

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