2011
DOI: 10.1016/j.ejcts.2011.04.017
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Mechanical circulatory support after heart transplantation

Abstract: Severe refractory heart failure after transplantation is a rare catastrophic event for which MCS offers the possibility of recovery or bridge to retransplantation, particularly for patients with biventricular failure in the absence of rejection. Early retransplantation should be considered in patients who show no evidence of graft recovery on MCS.

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Cited by 22 publications
(28 citation statements)
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“…Among the patients with severe PGD, 19 (61%) received effective salvage therapy and recovered. Previous studies have reported various rates of PGD after heart transplant (range, 2%‐26%) and salvage rates that were lower than the rate in our study . Some previous studies included smaller sample sizes, rendering the discrepancies in the incidence of PGD statistically nonsignificant.…”
Section: Discussioncontrasting
confidence: 76%
See 1 more Smart Citation
“…Among the patients with severe PGD, 19 (61%) received effective salvage therapy and recovered. Previous studies have reported various rates of PGD after heart transplant (range, 2%‐26%) and salvage rates that were lower than the rate in our study . Some previous studies included smaller sample sizes, rendering the discrepancies in the incidence of PGD statistically nonsignificant.…”
Section: Discussioncontrasting
confidence: 76%
“…The estimated incidence of moderate to severe PGD after heart transplant ranges from 2% to 26% . However, when PGD has been more strictly defined as the need for high‐dose inotropes or mechanical circulatory support in the immediate posttransplant period, most investigators have reported rates of 10%‐20% . This heterogeneity was addressed by the consensus statements of the International Society for Heart and Lung Transplantation (ISHLT) .…”
Section: Introductionmentioning
confidence: 99%
“…[226][227][228][229][230][231][232][233][234][235] The majority of published data describe the relatively successful use of extracorporeal membrane oxygenation (ECMO) in cases of primary graft failure. Although 30-day mortality is reduced in those who receive ECMO, in those who survive 30 days, long-term survival appears to be comparable to those who do not have primary graft failure.…”
Section: Mechanical Circulatory Support In Amr With Hemodynamic Comprmentioning
confidence: 99%
“…For heart recipients, graft failure has the potential to be life-threatening. Unlike kidney transplant recipients who are routinely treated with dialysis after graft failure, supporting a failing heart graft to successful retransplant is challenging (30)(31)(32)(33). While the use of extracorporeal membrane oxygenation and shortterm ventricular assist devices in acute graft failure have been described (31)(32)(33), the outcomes of patients with failing grafts supported with these technologies remain poor (30).…”
Section: Introductionmentioning
confidence: 99%