Mechanical characterization of nanofibers – A review

Tan, Eunice X.; Lim, Chwee Teck

doi:10.1016/j.compscitech.2005.10.003

Cited by 263 publications

(124 citation statements)

References 49 publications

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“…Specialized methods of testing individual fibers have been developed. Other authors have provided a more in depth review of mechanical characterization of individual nanofibers, 87 but the methods will be briefly described here to demonstrate the inherent difficulty.…”

Section: Mechanical Characterizationmentioning

confidence: 99%

“…The stage is used to apply tensile force to the fiber, and a microscope and camera are used to observe the fiber during testing. 87,88 A few commercial nanotensile testers have also been produced. One such system uses a cardboard frame to grip the nanofiber.…”

Section: Mechanical Characterizationmentioning

confidence: 99%

“…57,87 Obtaining and handling individual fibers are just a few of the difficulties. Further, specialized equipment is needed, such as a force transducer with high sensitivity and accuracy and an actuator with resolution large enough to precisely apply force.…”

Section: Mechanical Characterizationmentioning

confidence: 99%

“…Further, specialized equipment is needed, such as a force transducer with high sensitivity and accuracy and an actuator with resolution large enough to precisely apply force. 87 Due to these complications, mechanical testing of individual fibers is rarely performed. Despite these challenges, methods for tensile testing, bending, and nanoindentation of individual fibers have been reported.…”

Section: Mechanical Characterizationmentioning

confidence: 99%

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Polymeric Nanofibers in Tissue Engineering

Dahlin

Kasper

Mikos

2011

Tissue Engineering Part B: Reviews

294

198

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Polymeric nanofibers can be produced using methods such as electrospinning, phase separation, and selfassembly, and the fiber composition, diameter, alignment, degradation, and mechanical properties can be tailored to the intended application. Nanofibers possess unique advantages for tissue engineering. The small diameter closely matches that of extracellular matrix fibers, and the relatively large surface area is beneficial for cell attachment and bioactive factor loading. This review will update the reader on the aspects of nanofiber fabrication and characterization important to tissue engineering, including control of porous structure, cell infiltration, and fiber degradation. Bioactive factor loading will be discussed with specific relevance to tissue engineering. Finally, applications of polymeric nanofibers in the fields of bone, cartilage, ligament and tendon, cardiovascular, and neural tissue engineering will be reviewed.

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Section: Mechanical Characterizationmentioning

confidence: 99%

Section: Mechanical Characterizationmentioning

confidence: 99%

Section: Mechanical Characterizationmentioning

confidence: 99%

Section: Mechanical Characterizationmentioning

confidence: 99%

See 2 more Smart Citations

Polymeric Nanofibers in Tissue Engineering

Dahlin

Kasper

Mikos

2011

Tissue Engineering Part B: Reviews

294

198

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“…64 The atomic force microscopy (AFM) tip was positioned at the midpoint of the suspended nano-object, for measurement of object deflection (see Fig. 16).…”

Section: Mechanical Properties Of Polymer Nanofibersmentioning

confidence: 99%

Electrospun polymer nanofibers: Mechanical and thermodynamic perspectives

Arinstein

Zussman

2011

J Polym Sci B Polym Phys

137

103

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This article reviews and discusses some open problems concerning polymer materials of reduced sizes and dimensions. Such objects exhibit exceptional physical properties when compared with their macroscopic counterparts. More specifically, abrupt increases in polymer nanofiber elastic modulus have been observed when diameters drop below a certain value. In addition, temperature dependence of elastic modulus is highly influenced by fiber diameter. Mechanical (macroscopic) analyses have failed to provide satisfactory explanations for the mechanisms ruling such features, calling for detailed microscopic examination of the systems in question. A hypothesis bridging the current knowledge gaps is presented. The key element of this hypothesis is based on confinement of the supermolecular microstructure of polymer nanofibers and its dominant role in the deformation process. This suggestion challenges the commonly held view suggesting that surface effects are the most significant parameters impacting mechanical and thermodynamic nanofiber behaviors. The review will focus on the mechanical and thermodynamic properties of electrospun polymer nanofibers, selected as representatives of nanoscale polymer objects.

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References

2007

Science and Technology of Polymer Nanofibers

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Mechanical characterization of nanofibers – A review

Cited by 263 publications

References 49 publications

Polymeric Nanofibers in Tissue Engineering

Polymeric Nanofibers in Tissue Engineering

Electrospun polymer nanofibers: Mechanical and thermodynamic perspectives

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