Measuring the antioxidant capacity of serum in the neonatal period

Berger, HM

doi:10.1111/j.1651-2227.2001.tb03234.x

Cited by 1 publication

(1 citation statement)

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“…Ceruloplasmin is thought to possess extracellular antioxidant properties in humans and mammals (Halliwell and Gutteridge 1990; Krsek‐Staples and Webster 1993). In plasma, the iron, after oxidation to the ferric form by the ferroxidase activity of CP, is firmly bound to transferrin and these two proteins are supposed to be the antioxidants in serum (Berger 2001).…”

Section: Discussionmentioning

confidence: 99%

Antioxidants in Colostrum and Milk of Sows and Cows

Albera¹,

Kankofer²

2009

Reprod Domestic Animals

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On account of the oxidative stress conditions that may appear during parturition, colostrum should provide with not only nutritional and immunological components but also antioxidative protection of newborn. There is evidence that apart from well-known antioxidative enzymes like glutathione peroxidase, superoxide dismutase, catalase or low molecular antioxidants, proteins like lactoperoxidase (LPO), lactoferrin (LF) and ceruloplasmin (CP) may exert antioxidative properties in colostrum. The aim of present study was to determine and to evaluate LPO, LF and CP activities in colostrum and milk of sows and cows. Samples were collected from 16 healthy cows five times: immediately after parturition, 12, 24 and 48 h, and 7 days postpartum as well as from 14 healthy sows five times: immediately after parturition, 6, 12, 24 and 36 h later. Examined parameters were determined spectrophotometrically at 412, 560 and 540 nm respectively. LPO activity was higher in sows as in cows and increased significantly within examined time. LF ability to inhibit superoxide radical generation was higher in sows as in cows and increased significantly within examined time. CP oxidase activity was higher in cows as in sows and decreased significantly during experimental period. In conclusion, antioxidative defence system in colostrum shows dynamic changes that allow for providing with necessary protection from oxidative stress conditions, which may appear after parturition.

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Section: Discussionmentioning

confidence: 99%