The paper considers the development and experimental study of the characteristics of a high-temperature motion parameter sensor based on molecular-electronic technology (MET) operating at elevated pressures. Studies were conducted in an extended temperature range (25–125 °C) with a static external pressure of up to 10 atm. A pilot plant based on a high-pressure chamber with the ability to output an electrical signal was specially designed and commissioned. A family of amplitude-frequency characteristics of a ME sensor in an extended temperature range was obtained for the first time. A theoretical model was constructed and verified to describe the transfer function of the sensor at high temperatures and pressures. The activation energies of active carriers were calculated, and a prediction was made about the possibility of using the developed devices for the needs of the oil and gas mining industries.