Measurements of Articular Tissues With Ultrasound

Dussik, Karl Theo; Fritch, Donald J.; Kyriazidou, Marina; Sear, R.

doi:10.1097/00002060-195806000-00013

Cited by 73 publications

(20 citation statements)

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“…This is what we propose to do in a future study, either using magnetic resonance imaging (77)(78)(79)(80) or ultrasound characterisation (attenuation coefficient, backscatter coefficient) (81)(82)(83). With this latter system, several studies have already shown good correlation of increasing water content in the skin with decreasing attenuation coefficient (84)(85)(86).…”

Section: Hypo-echogenicitymentioning

confidence: 82%

Characterisation of gravity‐induced facial skin oedema using biophysical measurement techniques

Diridollou

Traon²,

Maillet³

et al. 2000

Skin Research and Technology

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Section: Hypo-echogenicitymentioning

confidence: 82%

Characterisation of gravity‐induced facial skin oedema using biophysical measurement techniques

Diridollou

Traon²,

Maillet³

et al. 2000

Skin Research and Technology

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“…The acoustic properties of the ink were assumed to be comparable to those of graphite 10 in the simulation, while the properties of the surrounding tissue were assumed to be linearly elastic and remain constant over the small range of temperatures experienced. The speed of sound in the tissue was specified as 1,498 m/second 26 and the density of the tissue defined as 1,100 kg/m 3 20. The in plane Young's modulus and Poisson's ratio for the ink were defined as 1.153 TPa and 0.195, respectively 27.…”

Section: Methodsmentioning

confidence: 99%

Finite element analysis of thermal and acoustic processes during laser tattoo removal

et al. 2012

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“…Ultrasonic attenuation of human and bovine cartilage was measured as early as the 1950s [20]. However, more comprehensive measurements of the anisotropic and heterogeneous properties of cartilage were not performed until the early 1990s, following a developed interest in the potential role of ultrasound for monitoring effects of osteoarthritis on cartilage.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound monitoring of cartilaginous matrix evolution in degradable PEG hydrogels☆

2009

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Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide conditions with varying distribution of the large cartilage extracellular matrix molecule, collagen. Mechanical properties and matrix accumulations were simultaneously measured for each condition during 9.5 weeks of in vitro culture. Ultrasound data were used to construct cross-sectional B-scan images for qualitative observations of evolving constructs. Ultrasound data were also analyzed to calculate the speed of sound (SoS) and slope of attenuation (SoA) in developing constructs and a non-degrading hydrogel control without encapsulated chondrocytes. SoS and SoA were calculated from 50 and 100MHz ultrasound data, and sample correlation coefficients were calculated to identify important relationships between these ultrasound parameters and mechanical/biochemical properties of the evolving matrix. SoA appears to be more sensitive to the density of accumulated matrix molecules than SoS, while SoS appeared to be more sensitive to mechanical modulus than SoA in measurements performed at 100MHz. Correlation analysis revealed that ultrasound measurements at 100MHz are more likely to be good predictors of matrix evolution and neotissue function than measurements at 50MHz. Rigorous studies of the relationships identified in this study will lead to non-destructive real-time monitoring that will be useful in combination with bioreactors used to promote and study cartilage regeneration.

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Measurements of Articular Tissues With Ultrasound

Cited by 73 publications

References 0 publications

Characterisation of gravity‐induced facial skin oedema using biophysical measurement techniques

Characterisation of gravity‐induced facial skin oedema using biophysical measurement techniques

Finite element analysis of thermal and acoustic processes during laser tattoo removal

Ultrasound monitoring of cartilaginous matrix evolution in degradable PEG hydrogels☆

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