Characterisation of gravity‐induced facial skin oedema using biophysical measurement techniques

Diridollou, S.; Traon, Anne Pavy-Le; Maillet, A.; Bellossi, F.; Black, David R.; Patat, F.; Lagarde, Jean‐Michel; Berson, M.; Gall, Y.

doi:10.1034/j.1600-0846.2000.006003118.x

Cited by 25 publications

(26 citation statements)

References 29 publications

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“…In simulated microgravity, there was an increase in facial dermal thickness and a decrease in skin stiffness. 22 It is unclear whether this change in facial skins including eyelid affected PPT-measured IOP. We believe it had affected little to our result as we could hardly find eyelid edema in the photos of our subject taken during spaceflight.…”

Section: Discussionmentioning

confidence: 99%

Diurnal Pattern of Intraocular Pressure is Affected by Microgravity When Measured in Space With the Pressure Phosphene Tonometer (PPT)

Chung

Woo

et al. 2011

Journal of Glaucoma

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Section: Discussionmentioning

confidence: 99%

Diurnal Pattern of Intraocular Pressure is Affected by Microgravity When Measured in Space With the Pressure Phosphene Tonometer (PPT)

Chung

Woo

et al. 2011

Journal of Glaucoma

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“…On the basis of these results, we believe that the cephalic fluid shift is a potent inhibitor for both passive and active cervical lymphatic pumps. Thus the facial edema observed during spaceflights (14,18,27) may be directly linked to the decreased lymphatic drainage of this region, which leads to increased lymph and interstitial pressures. In addition, the flow-induced inhibition of the active pump in cervical lymphatics was stronger after a 2-wk period of HDT.…”

Section: Discussionmentioning

confidence: 99%

“…Notably, the normal head-to-foot hydrostatic pressure gradients are eliminated and body fluids shift toward the head, resulting in a diminished fluid volume in the legs, facial edema, and increased fluid volume in the upper extremities (17,27,36,56,58). The facial puffiness common among astronauts and cosmonauts can persist wholly or partially for the duration of space missions lasting days, weeks, and months (14,18,27). Another important impact of microgravity is immune dysfunction.…”

mentioning

confidence: 99%

Inhibition of active lymph pump by simulated microgravity in rats

Gashev¹,

Delp²,

Zawieja³

2006

American Journal of Physiology-Heart and Circulatory Physiology

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During spaceflight the normal head-to-foot hydrostatic pressure gradients are eliminated and body fluids shift toward the head, resulting in a diminished fluid volume in the legs and an increased fluid volume in the head, neck, and upper extremities. Lymphatic function is important in the maintenance of normal tissue fluid volume, but it is not clear how microgravity influences lymphatic pumping. We performed a detailed evaluation of the influence of simulated microgravity on lymphatic diameter, wall thickness, elastance, tone, and other measures of phasic contractility in isolated lymphatics. Head-down tail suspension (HDT) rats were used to simulate the effects of microgravity. Animals were exposed to HDT for 2 wk, after which data were collected and compared with the control non-HDT group. Lymphatics from four regional lymphatic beds (thoracic duct, cervical, mesenteric, and femoral lymphatics) were isolated, cannulated, and pressurized. Input and output pressures were adjusted to apply a range of transmural pressures and flows to the lymphatics. Simulated microgravity caused a potent inhibition of pressure/stretch-stimulated pumping in all four groups of lymphatics. The greatest inhibition was found in cervical lymphatics. These findings presumably are correlated to the cephalic fluid shifts that occur in HDT rats as well as those observed during spaceflight. Flow-dependent pump inhibition was increased after HDT, especially in the thoracic duct. Mesenteric lymphatics were less strongly influenced by HDT, which may support the idea that lymph hydrodynamic conditions in the mesenteric lymphatic during HDT are not dramatically altered.

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“…Several non-invasive procedures are currently available for assessing the skin biomechanical changes due to oedema [11, 12, 13, 14, 15, 16, 17, 18]. Each of these approaches brings specific information [19].…”

Section: Introductionmentioning

confidence: 99%

Effect of Haemodialysis on Acoustic Shear Wave Propagation in the Skin

Uhoda¹,

Petit

Krzesinski

et al. 2004

Dermatology

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Background: Diverse skin alterations may develop in patients under chronic haemodialysis. Among them, signs of premature photo-ageing have been described. Aim: To assess alterations in the physical properties of skin consistent with ageing effects and with cutaneous fluid exchanges during haemodialysis sessions. Methods: In the first part of the study, 45 haemodialysed patients were compared to 45 age-, sex- and body-mass-index-matched healthy subjects. In the second part of the study, skin of 30 haemodialysed patients was assessed immediately before and after a haemodialysis session. The speed of ultrasound shear wave propagation was measured in each subject. Series of 16 multidirectional resonance running time measurements (RRTM) were performed on the forehead and/or the volar forearm. They were averaged for each subject. The corresponding intra-individual coefficients of variation were calculated as an estimate of the skin mechanical anisotropy. Results: In both haemodialysed patients and their matched controls, RRTM values were significantly higher on the forearms than on the forehead. By contrast, no significant difference was found in RRTM values that could be ascribed to chronic haemodialysis. However, RRTM values were significantly increased as an immediate and probably transient effect of haemodialysis sessions. In healthy subjects, ageing was associated with increased RRTM values. Conclusion: Chronic haemodialysis does not appear to influence significantly the functional expression of the dermal ageing process. Subtle fluid movements occurring in the skin during haemodialysis sessions can be assessed by measuring non-invasively the speed of ultrasound shear wave propagation in the skin.

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Characterisation of gravity‐induced facial skin oedema using biophysical measurement techniques

Cited by 25 publications

References 29 publications

Diurnal Pattern of Intraocular Pressure is Affected by Microgravity When Measured in Space With the Pressure Phosphene Tonometer (PPT)

Diurnal Pattern of Intraocular Pressure is Affected by Microgravity When Measured in Space With the Pressure Phosphene Tonometer (PPT)

Inhibition of active lymph pump by simulated microgravity in rats

Effect of Haemodialysis on Acoustic Shear Wave Propagation in the Skin

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