Measurement of Coronary Blood Flow and Cardiac Efficiency in Hypothermia by Use of Radioactive Krypton 85

Hansen, Ann‐Brit Eg; Haxholdt, B F; Husfeldt, E; Lassen, Niels A.; Munck, O.; Sørensen, H.; Winkler, K.

doi:10.3109/00365515609049269

Cited by 22 publications

(4 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The cerebral oxygen uptake and the cerebral perfusion are reduced roughly in proportion to the reduction in total body oxygen uptake, cardiac output, pulse rate, and myocardial and renal blood flow. These values all decrease to about 50 per cent of the normal levels at a temperature of 28OC (134,222,263,296 This correlation was first noted by Kety, who stated: 'CIn all of our studies we have been impressed with the close correlation between the level of consciousness and the rate of oxygen consumption by the brain. In patients who are comatose for whatever reason, cerebral oxygen consumption falls to a value of less than 2.0 cc per I oo gm per minute, while in those who are semistuperous or confused, the value lies between 2.5 and 3.0" (156).…”

Section: Downloaded Fromsupporting

confidence: 57%

Cerebral Blood Flow and Oxygen Consumption in Man

Lassen¹

1959

Physiological Reviews

1,812

950

View full text Add to dashboard Cite

show abstract

Section: Downloaded Fromsupporting

confidence: 57%

Cerebral Blood Flow and Oxygen Consumption in Man

Lassen¹

1959

Physiological Reviews

1,812

950

View full text Add to dashboard Cite

show abstract

“…2 A the activity in cpm is directly proportional to the tissue concentration of Krss and myocardial blood flow can thus be calculated as above. T h e half time of decay is 31 sec which gives a coronary blood flow of 126 ml/min/100 g if the specific weight of the myocardium is set a t 1.05 and 2 assumed to be 1 .O (Hansen et al 1956, Herd et al 1962.…”

Section: Resultsmentioning

confidence: 99%

Collateral Blood Flow in the Myocardium of Dogs Measured with Krypton⁸⁵

Johansson¹,

Linder²,

Seeman³

1964

Acta Physiologica Scandinavica

View full text Add to dashboard Cite

Johansson, B., E. Linder and T. Seeman. Collateral blood flow in the myocardium of dogs measured with Krypton85. Acta physiol. scand. 1964. 62. 263–270. — Methods have recently been developed for determination of regional blood flows from wash‐out curves recorded externally after close‐arterial injection of radioactive Krypton (Kr85). In the present study this technique has been applied to measurement of collateral capillary blood flow in the myocardium of dogs during acute occlusions of coronary arteries. A monoexponential fall in activity was found during elimination of Krypton from the normal myocardium indicating a homogeneous distribution of blood flow. The wash‐out curves recorded during coronary occlusions could be dissolved into two separate components. There was a rapid phase related to the elimination of Krypton from normally perfused regions of the myocardium and a slow phase due to the de‐saturation of the ischemic portion. The magnitude of the collateral capillary blood flow was determined from the decay rate of the slow component. The relative size of the ischemic region could be estimated from the zero time values of the two phases. Collateral blood flow seemed to be fairly homogeneously distributed within the ischemic part of the myocardium. Release of an occlusion was followed by a rapid fall in activity in association with the reactive hyperemia.

show abstract

“…Benutzt wurden dabei Krypton-85 [70,177], Jod-131-Antipyrin [69,117] [25,195,196]. Benutzt wurden dabei Krypton-85 [70,177], Jod-131-Antipyrin [69,117] [25,195,196].…”

Section: Die Kety-schmidt-methode Und Ihre Variantenunclassified

Wert und Grenzen klinischer Koronardurchblutungsmessungen

Tauchert¹

1975

Klin Wochenschr

View full text Add to dashboard Cite

Attempts to measure coronary blood flow in man have made considerable progress during the last 25 years. The major techniques are based on the direct or indirect Fick principle; coronary flow is calculated from the arterio-coronary venous difference of inert gases or from the precordial recorded disappearance curve of radioactive gases or substances. The accuracy of the techniques depends upon the properties or the indicators used and the precision of their determination. All techniques applied hitherto are intricate and unsuitable for general use. -A lot of information is obtained about coronary circulation in health and disease by coronary flow measurements in man. Further studies in this field may influence pathophysiological and clinical concepts especially concerning coronary heart disease.

show abstract

Measurement of Coronary Blood Flow and Cardiac Efficiency in Hypothermia by Use of Radioactive Krypton 85

Cited by 22 publications

References 12 publications

Cerebral Blood Flow and Oxygen Consumption in Man

Cerebral Blood Flow and Oxygen Consumption in Man

Collateral Blood Flow in the Myocardium of Dogs Measured with Krypton⁸⁵

Wert und Grenzen klinischer Koronardurchblutungsmessungen

Contact Info

Product

Resources

About

Measurement of Coronary Blood Flow and Cardiac Efficiency in Hypothermia by Use of Radioactive Krypton 85

Cited by 22 publications

References 12 publications

Cerebral Blood Flow and Oxygen Consumption in Man

Cerebral Blood Flow and Oxygen Consumption in Man

Collateral Blood Flow in the Myocardium of Dogs Measured with Krypton85

Wert und Grenzen klinischer Koronardurchblutungsmessungen

Contact Info

Product

Resources

About

Collateral Blood Flow in the Myocardium of Dogs Measured with Krypton⁸⁵