The article is devoted to the investigation of a pd reaction (p + d 3 He + γ(5.5 MeV)) under going in titanium deuteride in astrophysical collision energy region of protons and deuterons ranging from 5.3 to 10.5 keV. The experiments have been performed using the Hall NR TPU (Tomsk, Russia) pulsed plasma accelerator. The number of accelerated protons in 10 μs pulse was 5 × 10 14 at a repetition rate of 7 × 10 -2 Hz. Detection of 5.5 MeV gamma rays was carried out using eight detectors based on crystals of NaI(Tl) (100 × 100 × 400 mm) placed around the TiD target. For the first time, the dependencies between the astro physical S factor and the effective cross section of the pd reaction from proton-deuteron collision energy, and the potential electronic screening of the interacting protons and deuterons in titanium deuteride have been measured.