Measurement and Correlation for Solubility of (S)-(+)-2,2-Dimethyl-cyclopropane Carbox Amide in Different Solvents

In this study, the solubility of cefathiamidine was measured in water + (acetone, ethanol, or 2-propanol) at temperature from (278.15 to 313.15) K by using a gravimeteic method. The solubility of cefathiamidine increased with increasing temperature. Besides, at a given temperature, solubility in different mixtures follows different rules. In water + (acetone or 2-propanol), it decreases with the increase of the initial molar fraction of acetone or 2-propanol; whereas synergistic effect of mixed solvents was observed in water + ethanol mixtures, and solubility reached maximum at the ethanol molar fraction of 0.4. The experimental data were well correlated by the modified Apelblat equation, the CNIBS/R-K model, the combined version of the Jouyban−Acree and van't Hoff model, and the combined version of the Jouyban−Acree and the modified Apelblat model. Furthermore, the thermodynamic functions of dissolution of cefathiamidine in different mixtures were obtained based on the van't Hoff equation and the modified Apelblat equation. The results indicate that the dissolution process of cefathiamidine is endothermic.

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“…Modified Apelblat Equation. The modified Apelblat equation 12 is a semiempirical model, which depends on temperature…”

Section: Resultsmentioning

confidence: 99%

Measurement and Correlation of Solubility of Cefathiamidine in Water + (Acetone, Ethanol, or 2-Propanol) from (278.15 to 308.15) K

et al. 2015

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“…The equation can be shown as follows: In this equation, x 1 refers to the mole fraction solubility of the solute; T is the absolute experimental temperature, and A , B , and C are equation parameters. A and B are constants which are in accordance with the nonideality of the real solution, and C reveals the effect of temperature on the fusion enthalpy …”

Section: Thermodynamic Equationsmentioning

confidence: 97%

“…A and B are constants which are in accordance with the nonideality of the real solution, and C reveals the effect of temperature on the fusion enthalpy. 14 3.2. λh Equation. λh equation was proposed by Buchowski et al 15,16 Like the Apelblat equation, λh equation also reflects the relationship between the mole fraction solubility x 1 and temperature T. It can be shown as follows:…”

Section: Thermodynamic Equationsmentioning

confidence: 99%

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Measurement and Correlation of the Solubility of Azoxystrobin in Seven Monosolvents and Two Different Binary Mixed Solvents

Yang

Zhang

et al. 2017

J. Chem. Eng. Data

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A gravimetric method was used to determine the solubility of azoxystrobin in seven monosolvents (methanol, ethanol, n-propanol, isopropanol, n-butanol, isobutanol, and ethyl acetate) and two binary mixed solvents (n-propanol + ethyl acetate and methanol + ethyl acetate) at different temperatures from 288.15 to 328.15 K. The solubility of azoxystrobin is positively related with temperature in all selected solvents. Moreover, the solubility of azoxystrobin in methanol + ethyl acetate binary mixed solvent reaches a maximum when the mole fraction of ethyl acetate is 0.8, differing from that in n-propanol + ethyl acetate binary mixed solvent. The Apelblat, λh, combined nearly ideal binary solvent/ Redlich−Kister, and nonrandom two-liquid model (NRTL) equations were applied to correlate the solubility of azoxystrobin, and all of the equations provided good fitting results to the data. In addition, the mixing thermodynamic properties of azoxystrobin in binary mixed solvents were calculated based on the NRTL equation. The results demonstrate that the mixing process in the experimental binary mixed solvents is endothermic and spontaneous.

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“…97-99, December 2017 ISSN: 2354-2144 Short Communication penetrating the vessel reached the maximum, and the temperature was recorded. The solubility expressed by mole fraction was calculated as follows (Shi et al, 2006).…”

Section: African Journal Of Engineering Researchmentioning

confidence: 99%

Measurement and correlation of solubility of β-cyclodextrin in sucrose solution

Li¹

2017

Afr J Eng Res

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Measurement and Correlation for Solubility of (S)-(+)-2,2-Dimethyl-cyclopropane Carbox Amide in Different Solvents

Cited by 19 publications

References 4 publications

Measurement and Correlation of Solubility of Cefathiamidine in Water + (Acetone, Ethanol, or 2-Propanol) from (278.15 to 308.15) K

Measurement and Correlation of Solubility of Cefathiamidine in Water + (Acetone, Ethanol, or 2-Propanol) from (278.15 to 308.15) K

Measurement and Correlation of the Solubility of Azoxystrobin in Seven Monosolvents and Two Different Binary Mixed Solvents

Measurement and correlation of solubility of β-cyclodextrin in sucrose solution

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