Measles Outbreak in Sverdlovsk Region

Скрябина, С. В.; Ковязина, С. А.; Кузьмин, С В; Юровских, А. И.; Цвиркун, О. В.; Герасимова, А. Г.; Тихонова, Н. Т.; Малямова, Л. Н.; Smirnova, S.S.; Харитонов, А Н; Рыбинскова, Э. А.

doi:10.31631/2073-3046-2018-17-2-50-56

Cited by 4 publications

(7 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Measles in all the age groups of children, both vaccinated and unvaccinated, typically occurred with a predominance of moderately seve-re course of the disease. Our results in terms of the disease severity do not have significant differences with data from other studies (Pavelkina et al, 2016;Skryabina et al, 2018;Smyrnova et al, 2019). Analysis of the obtained data shows that the severe course of the disease (29.3%) occurs at all ages, but among children with severe course there are two times more infants up to one year and preschool children than schoolchildren (64.5% and 35.5% respectively).…”

Section: Discussionsupporting

confidence: 50%

“…According to our observations, the pathognomonic symptoms of measles -enanthema (30.2%) and Belsky-Filatov-Koplik spots (40.6%)were three times more frequent in children under 6 years of age than in schoolchildren (63.9% and 23.3%, respectively, Р < 0.05). According to literature data (Pokrovska et al, 2015;Timchenko et al, 2017;Skryabina et al, 2018) Belsky-Filatov-Koplik spots are more frequently found, in 66.5-96.8% of patients. Kharchenko & Kimirilova (2019) point out that Belsky-Filatov-Koplik spots are observed in 66.5% of patients, including half of the children under one year and 77.5% of schoolchildren.…”

Section: Discussionmentioning

confidence: 98%

“…The works of Clemmons et al (2017), Skryabina et al (2018), Nickovic et al ( 2019) report an increase in the proportion of diseased schoolchildren aged 6-14 and adolescents. According to Usacheva et al ( 2019) the proportion of children aged 1-9 years of all measles diseased children in the Zaporizhzhya region is 72%, in the Carpathian region diseased children of this age amount to 64.8%, which indicates low vaccination coverage (Savchuk et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

“…The leaders in the number of measles patients in 2018 in Ukraine were Lviv, Ivano-Frankivsk, Transcarpathian, Ternopil and Chernivtsi regions (Koloskova et al, 2019). In Ukraine, the increase in the incidence rate in recent years is primarily associated with low vaccination rates (Skryabina et al, 2018;Smyrnova et al, 2019). In 2016, only 45% of children in Ukraine had measles vaccinations.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Epidemiology and features of the measles course in children during the outbreak of 2018–2019 in the city of Mariupol

Koniushevska

Parkhomenko

Sharunova³

et al. 2020

Regul. Mech. Biosyst.

View full text Add to dashboard Cite

In 2017, Ukraine ranked in the top three among European countries in terms of measles incidence, and ranked first in measles growth in 2018. High morbidity, mortality and development of complications make the problem of knowing features of the measles clinical course, timely diagnosis and active prevention highly relevant. The purpose of the research is to study the dynamics of the incidence and clinical features of measles in children during the outbreak of 2018–2019 in the city of Mariupol, Donetsk region. A peculiarity of the measles outbreak in 2018–2019 in Mariupol is prevalence of the disease in preschool children (60.4%), including 30.2% – those under one year of age; low vaccination rate: 52.3% of children unvaccinated; only 22.2% of children were vaccinated twice, according to the schedule. In all age groups, a moderately severe measles course prevailed (69.8%). The clinical course of measles in preschool and school age children had definitive features. Thus, Belsky–Filatov–Koplik spots were observed three times more frequently in preschool children than in schoolchildren (63.9% and 23.3%, respectively). Abdominal pain and diarrhea were only observed in children under 6 years of age (30.2%). Skin pigmentation was absent in children under one year of age and was detected in preschool and school-age children (69.8%). Skin sloughing was only observed in schoolchildren (10.4%). Severe disease course occurred in patients of all ages (29.3%), but children aged under one year and preschool children with severe disease were two times more numerous than those of the school age. Among the observed complications, the vast majority were associated with the respiratory organs: pneumonia (38.3%), subcutaneous emphysema (1.7%), bronchitis (53.2%), laryngitis (3.3%), otitis media (5%). No fatalities were observed. The city should form a commitment to immunization, restore public trust in vaccination, using all forms and means of information, and develop a program to implement the vaccination schedule into practice.

show abstract

Section: Discussionsupporting

confidence: 50%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Epidemiology and features of the measles course in children during the outbreak of 2018–2019 in the city of Mariupol

Koniushevska

Parkhomenko

Sharunova³

et al. 2020

Regul. Mech. Biosyst.

View full text Add to dashboard Cite

show abstract

“…Учитывая, что территория РФ является неблагополучной относительно эпидемической напряженности по гриппу [21,22], низкий охват детского населения прививками, несомненно, влечет за собой развитие вспышек данного заболевания [23,24]. Подобные последствия низкого охвата вакцинацией, приводящие к росту заболеваемости от вакциноуправляемых инфекций, можно увидеть на примере коревой и коклюшной инфекций [25,26]. Также следует подчеркнуть достаточно большое количество нарушений в схеме вакцинации и ее несвоевременное проведение.…”

Section: интерпретация результатов исследованияunclassified

Immunization and Immunization Coverage According to National Immunization Schedule for Children Population: Cross-Sectional Multi-Centre Study

et al. 2021

View full text Add to dashboard Cite

Background. Monitoring of documented vaccination is one of the indicators of the epidemiological supervision quality of preventive vaccination. It is crucial for epidemical situation prevention. Objective. The aim of the study is to estimate immunization and immunization coverage levels according to National Immunization Schedule (NIS) for children population in Russia. Methods. Immunization rates were estimated according to preventive vaccination cards (form №063/y) and children development cards (form №112/y) among children aged from 6 months to 15 years in 8 towns of Russia. Immunization was determined by the ratio of people who has fully performed all the vaccines from NIS (version of the year 2014), while immunization coverage – by the ratio people who has received at least one dose of corresponding vaccine. Results. The study has included data from 2,687 vaccinated children. The highest levels of immunization and immunization coverage were against tuberculosis (98.1% each), hepatitis B (85.9% and 96.5%), measles, mumps and rubella (84.4% and 93.9%). Immunization against diphtheria, pertussis and tetanus significantly differed from their immunization coverage (60.5% and 94.9%), as well as for poliomyelitis (65.0% and 94.9%). Relatively low immunization and immunization coverage levels were observed for pneumococcal infection (27.6% and 47.1%) and influenza (5.8% and 30.5%). The increase in the immunization level with age was observed for all vaccines, except pneumococcal vaccine. Conclusion. Immunization and immunization coverage against infections included in NIS vary significantly. The highest immunization and immunization coverage levels for all age groups were revealed for tuberculosis vaccine, and the lowest — for influenza vaccine.

show abstract

Multi-Factor Simulation Modeling in the Short-and Long-Term Prognosis of Measles Incidence

Platonova

Голубкова

Obabkov

et al. 2018

Epidemiology and Infectious Diseases

View full text Add to dashboard Cite

The widespread increase in morbidity and the registration of major measles outbreaks in recent years require the development of new technologies to control the infection. Technologies should be based on the prognosis of morbidity. The aim of the study was to predict the development of the situation in the near and long term in order to determine the adequate technologies of infection control in the metropolis at the stage of its elimination on the basis of a mathematical simulation of the epidemic process of measles. Materials and methods. A simulation model to forecast the incidence of measles was developed using special software AnyLogic Professional 7.0. The model included the main determinants of the epidemic process, established by the results of their own research and literature data. The results of the epidemic process modeling were uploaded to the database. Further work was carried out in the database management system Microsoft SQL Server Management Studio. Analysis and graphical processing of the results are performed using comprehensive software for business intelligence Power BI. Results. It is established that at low (50-60%) coverage of vaccinations of children in the decreed ages and the population as a whole, the probability of measles outbreaks is high both in the short and long term. The increase in vaccination coverage to 90-95% leads to an increase in the period of epidemic well-being, but the likelihood of an outbreak remains. With revaccination every 10 years, at least 60% of the population remains stable for 30 years and the spread of infection does not occur. With the coverage of revaccinating vaccinations 80% of the population-the epidemiological situation remains stable for 50 years. Conclusion. The simulation model of measles morbidity forecast for the near and long term, built with the main determinants of the epidemic process, allows us to predict the development of the epidemic situation in the territory of a large industrial city. Also, the model allows to determine the priority areas for the elimination of measles infection, namely: strict control of the timeliness and completeness of vaccination coverage of children in the decreed age (at least 95%) and maintaining a high immune layer of the population as a whole, which can be provided during the planned revaccination against measles every 10 years.

show abstract

Measles Outbreak in Sverdlovsk Region

Cited by 4 publications

References 8 publications

Epidemiology and features of the measles course in children during the outbreak of 2018–2019 in the city of Mariupol

Epidemiology and features of the measles course in children during the outbreak of 2018–2019 in the city of Mariupol

Immunization and Immunization Coverage According to National Immunization Schedule for Children Population: Cross-Sectional Multi-Centre Study

Multi-Factor Simulation Modeling in the Short-and Long-Term Prognosis of Measles Incidence

Contact Info

Product

Resources

About