Mean platelet volume: A novel prognostic factor of rotavirus gastroenteritis?

Karagöz, Ergenekon; Tanoğlu, Alpaslan

doi:10.3109/09537104.2014.898179

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…In line, AST level has been significantly associated with IL-6 (16) and mean platelet volume (13,21) in previous studies on patients with AGE. The clinical significance of inflammatory markers in elevation of liver enzymes in AGE patients should be investigated more (15,22).…”

Section: Discussionsupporting

confidence: 65%

A Survey on the Fluctuations of Liver Enzymes in Severely Dehydrated Children with Acute Gastroenteritis

et al. 2019

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Background: Acute gastroenteritis (AGE) is a potential life-threatening condition in young children. Objectives: Our aim was to assess hepatic enzymes levels in children with AGE and severe dehydration (> 10%). Methods: We enrolled 138 children with AGE admitted to the Amir-Al-Momenin Hospital of Zabol city in 2016. Children with severe dehydration (> 10%), according to the Vesikari score, were included. Complete blood count, selected inflammatory markers, and hepatic enzymes were investigated.Results: Males and females comprised 89 (64.5%) and 49 (35.5%) of the cases, respectively. The mean age was 3 ± 2.7 years old. Concomitant aspartate aminotransferase (AST) and alanine aminotransferase (ALT) elevation and isolated AST elevation were observed in 22 (15.9%) and 60 (43.5%) of the patients, respectively. Normal AST and ALT levels were observed in 56 (40.6%) of the patients. The AST level significantly correlated with age (r = -0.230, P = 0.007) and platelet count (r = 0.184, P =0.03). Significant correlations were also detected between ALT level and age (r = -0.230, P = 0.007), ESR (r = -0.240, P = 0.03), and K + level (r = 0.244, P = 0.03). Conclusions: Our results highlighted relatively high frequency of elevated liver enzymes in severely dehydrated children with AGE.

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Section: Discussionsupporting

confidence: 65%