MDGA1-deficiency attenuates prepulse inhibition with alterations of dopamine and serotonin metabolism: An ex vivo HPLC-ECD analysis

Hossain, Razib; Jamal, Mostofa; Yu, Tanoue; Ojima, Daiki; Takahashi, Hiroo; Kubôta, Takashi; Ansary, Tuba M.; Ito, Asuka; Tanaka, Naoko; Kojima, Hiroshi; Kishimoto, Yasushi; Yamamoto, Tohru

doi:10.1016/j.neulet.2019.134677

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Feasibility Of the Vfc To Genetically Modified Mice1

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Cited by 5 publications

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“…2 Its null-mutant mice showed learning deficit in the contextual FC, water maze, 3 and prepulse inhibition of the startle response. 10 We tried to apply this new method for learning in the heterozygous Mdga1-mutant mice in which the amount of MDGA1 becomes around half. 11 The result indicates that these heterogenic mutant mice showed deficit also in this paradigm of learning (Figure 3).…”

Section: Feasibility Of the Vfc To Genetically Modified Micementioning

confidence: 99%

Visually cued fear conditioning test for memory impairment related to cortical function

Kuboyama

Yuki

Kawada

et al. 2020

Neuropsychopharm Rep

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Fear conditioning (FC) describes a learning and memory paradigm in which an animal's ability to acquire and retrieve an association between a conditioned stimulus (CS), such as a place in contextual FC or tone in auditory FC, and an unconditioned stimulus (US), such as footshock or corneal air puff, is assessed. Fear conditioning memory is indexed by quantitation of a behavioral response, such as time

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