Maximal amniotic fluid index as a prognostic factor in pregnancies complicated by polyhydramnios

Pri-Paz, Shai; Khalek, Nahla; Fuchs, Karin; Simpson, Lynn L.

doi:10.1002/uog.10093

Cited by 77 publications

(89 citation statements)

References 22 publications

(27 reference statements)

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“…It causes the decrease production of amniotic fluid by increase absorption of fluid by lungs, reducing the urine output and also impairs the prostaglandin mediated response of renal vasculature 7,10,11 . The frequency of polyhydramnios was 1.7% in our study which corresponds with the other study mentioned in literature which showed the incidence of 1-2% respectively [2][3][4][5][6] . The causes of polyhydramnios in our study was mainly idiopathic which was similar to study performed by Maymon et al 12 , Tariq S et al 13 and Panting Kemp et al 14 .…”

Section: Discussionsupporting

confidence: 90%

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Role of indomethacin in polyhydramnios

Shrestha¹,

Chawla

2013

Sri Lanka J Obstet & Gynae

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Objective: To observe the role of indomethacin in polyhydramnios.Method: This was a prospective, longitudinal and analytical study conducted in Kathmandu University Hospital, Dhulikhel from 1st July 2011 to 1st of December 2012. There were 32 patients included in the study. Indomethacin was administered orally at the dose of 25 mg three times a day for 1 week. The patients were admitted for observation of clinical symptoms, fundal height, fetal status and amniotic fluid index measurement. After the delivery, baby was investigated for any abnormality of fetal circulation.Results: There were total of 2700 deliveries in 1 year. Among them 46 cases were of polyhydramnios. The frequency was 1.7%. Among the 46 cases, 32 (69.6%) were idiopathic who were included whereas 8 (17.4%) were of diabetes mellitus, 4 (8.7%) were Rh isoimmunisation, and 2 (4.3%) were fetal anomalies. The mean age group was 24.5+/ -4.2 years. There were total 10 (31.3%) patients presented at 29 weeks of gestation whereas only 5 (15.7%) patients at 32 weeks of gestation. Regarding the gravid index, 17 (53.1%) patients were primigravida. There was statistically significant reduction in amniotic fluid volume following 1 week administration of indomethacin. Conclusion:Though there are many modes of treatment for polyhydramnios, the 1 week therapy with indomethacin is equally beneficial.

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Section: Discussionsupporting

confidence: 90%

“…Polyhydramnios is one of the dreaded complication in obstetric practice, as it affects not only mother but also the fetus. The overall incidence is 1-2% [2][3][4][5][6] . It causes maternal complications like antepartum hemorrhage, respiratory embarrassment, abnormal presentation, uterine dysfunction and also postpartum hemorrhage.…”

Section: Introductionmentioning

confidence: 99%

Role of indomethacin in polyhydramnios

Shrestha¹,

Chawla

2013

Sri Lanka J Obstet & Gynae

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“…It is well known, that polyhydramnios is associated with the increased risk of different fetal congenital anomalies [3][4][5].…”

Section: Discussionmentioning

confidence: 99%

“…It seems that not only the finding of polyhydramnios, but also the value of AFI have a significant effect on a fetal and neonatal outcome, including the frequency of birth defects [3,4]. Congenital anomalies were most frequently found in pregnancies complicated by severe polyhydramnios [4].…”

Section: Introductionmentioning

confidence: 99%

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Polyhydramnios — frequency of congenital anomalies in relation to the value of the amniotic fluid index

Kornacki

Adamczyk²,

Wirstlein³

et al. 2017

Ginekol Pol

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Objectives: The aims of our study were to assess the correlation between the amniotic fluid index (AFI) value and the frequency and type of fetal anomalies. Material and methods:The material included 94 patients at the third trimester of pregnancy, 60 with mild polyhydramnios, 19 with moderate one, and 15 with severe one. Polyhydramnios was diagnosed if AFI was > 24 cm. All patients were divided into three groups based on the value of AFI: 1) mild polyhydramnios with AFI between 24.1 and 29.9 cm, 2) moderate polyhydramnios with AFI between 30-34.9 cm, and 3) severe polyhydramnios with AFI ≥ 35 cm. Results:The incidence of fetal malformations correlated significantly with the degree of polyhydramnios and was the highest in patients with severe polyhydramnios (53.3%, p = 0.002). Congenital malformations of the gastrointestinal tract were the most frequent fetal anomalies in the whole group of patients (5.3%). Trisomy 18 was the most frequent aneuploidy found in women with polyhydramnios (2.1%). Conclusions:1. The incidence of fetal congenital anomalies significantly increases with the degree of polyhydramnios, being most frequent in severe one and rather rare in a mild one. 2. Congenital malformations of the gastrointestinal tract were the most frequent anomalies in patients with polyhydramnios, especially in women with severe polyhydramnios.

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