“…The host defense system gets by the presence of any immunocompromising condition like Diabetes mellitus, leukemia, malnutrition, agranulocytosis, severe anemia, chronic alcoholism, drug abuse, sickle cell disease, typhoid, chemotherapy, irradiation, steroid use, hepatitis, HIV, glomerulonephritis, systemic lupus erythematosus, etc. 1,3,13 The vascularity of the host bone is altered due to therapeutic irradiation, Paget's disease, bone malignancy, fibrous dysplasia, osteoporosis, mercury; arsenic, and bismuth causing metallic bone necrosis. In the maxilla, osteomyelitis can occur due to any pansinusitis or facial cellulitis.…”