1994
DOI: 10.1159/000276612
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Maturational Aspects of the Human Auditory Pathway: Anatomical and Electrophysiological Findings

Abstract: Anatomical investigations were carried out on 39 human brains ranging in age from the 29th week of development to the 70th year of life. It was demonstrated that myelination, as a prerequisite for functional maturation, takes place during the 1 st year of life. Functional maturation was analyzed with electrophysiological techniques. Normal development depends on adequate stimulation during certain sensitive periods in the 1st year of life as well as on the continuous use of the central auditory and speech-hear… Show more

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Cited by 15 publications
(4 citation statements)
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References 7 publications
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“…A functional MRI study has revealed that the degree of synchronization was lower for the autistic than for others. This functional under connectivity could be due to microgliosis and astrogliosis [21] and can result in delayed nerve conduction [22]. It may explain the relatively increased doses of sedatives to achieve the desired level in autistic patients.…”
Section: Discussionmentioning
confidence: 99%
“…A functional MRI study has revealed that the degree of synchronization was lower for the autistic than for others. This functional under connectivity could be due to microgliosis and astrogliosis [21] and can result in delayed nerve conduction [22]. It may explain the relatively increased doses of sedatives to achieve the desired level in autistic patients.…”
Section: Discussionmentioning
confidence: 99%
“…These intervals reflect trans-synaptic transmission. Matschke, Stenzel, Plath, and Zilles [ 19 ], in a study of 39 human brains ranging in age from 29 weeks of gestation to 70 years, demonstrated that myelination takes place in the first year of life which is necessary for functional maturation. It appears that normal auditory development is dependent on adequate stimulation during this sensitive period of life.…”
Section: Introductionmentioning
confidence: 99%
“…Die Eltern [7], gegebenenfalls auch das Kind selbst [5] sollten darauf hingewiesen werden, bei plötzlicher Akzeptanzveränderung baldmöglichst eine aktuelle Kontrolle zu veranlassen: Neben Hörgerätemängeln, Cerumen, otoplastikbedingten Reaktionen im äuße-ren Gehörgang und die im Kindesalter besonders häufigen mittelohrbedingten Hörstörungen wäre hierbei eine In unserem Patientengut war eine nicht korrekte Otoplastikform der Grund für 9% aller Mängel, wobei ein Hörschwellenänderung, etwa im Sinne einer Nachreifung der Hörbahn oder einer Progredienz auszuschließen [8,11,13,15].…”
Section: Introductionunclassified