Matrix solid phase dispersion (MSPD)

Barker, Steven A.

doi:10.1016/j.jbbm.2006.06.005

Cited by 366 publications

(165 citation statements)

References 195 publications

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“…This technique combines sample preparation, extraction, and fractionation into one process, limiting the handling and transfer steps [184]. The sample is mechanically ground with a bounded-phase solid support material in a mortar and then packed into a chromatographic column to isolate the carotenoids of interest.…”

Section: Solvent Extractionmentioning

confidence: 99%

New Developments in Lycopene Analysis by Spectroscopic and Chromatographic Techniques, Accompanied With Mathematical Modelling

Cáceres¹,

Cámara²,

Manzoor³

et al. 2015

Acta Hortic.

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Section: Solvent Extractionmentioning

confidence: 99%

New Developments in Lycopene Analysis by Spectroscopic and Chromatographic Techniques, Accompanied With Mathematical Modelling

Cáceres¹,

Cámara²,

Manzoor³

et al. 2015

Acta Hortic.

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“…MSPD is a process for the simultaneous disruption and extraction of solid or semisolid samples, involving the blending of a solid support material with a sample, then transferring into an empty column or the top of the column which was packed with the same support material at the bottom of the column to obtain a further extraction and sample clean-up [22]. The main difference between MSPD and SPE is that the sample is not only absorbed onto the top of the column packing material in MSPD, but also dispersed throughout the column [23]. Extraction and clean-up can be performed simultaneously with the MSPD method.…”

Section: Introductionmentioning

confidence: 99%

Selective separation of flavonoid glycosides in Dalbergia odorifera by matrix solid‐phase dispersion using titania

Shi

Liang

et al. 2011

J of Separation Science

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Dalbergia odorifera contains high concentrations of flavonoid aglycones and trace flavonoid glycosides. In this study, trace flavonoid glycosides were separated from D. odorifera by titania with matrix solid-phase dispersion (MSPD). Before the MSPD experiment, four standards, including two isoflavone glycosides (genistin and formononetin-8-C-apiosyl (1-6)-glucoside) and their aglycones (genistein and formononetin), were used to compare their retention on a titania column. The effect of acetonitrile concentration and pH on their retention was investigated and a conclusion was drawn that high acetonitrile concentration and pH lead to the greatest difference in the retention of flavonoid as glycosides and aglycones. Besides hydrophilic interaction and ligand-exchange interaction may exist between sugar moiety of flavonoid glycoside and titania, so that flavonoid glycosides have stronger retention than that of aglycones. Based on the chromatographic rule of flavonoid as glycosides and aglycones on the titania column, the MSPD method was optimized to elute high concentration flavonoid aglycones first with 90% acetonitrile and 10% water containing 100 mM ammonium acetate buffer, and then to elute trace flavonoid glycosides with 20% acetonitrile and 80% water containing 1% trifluoroacetate (TFA). Isolated flavonoid glycosides were further analyzed by UPLC-MS/MS, and their fragmentation in MS 2 showed they are C-glycosyl flavonoids.

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“…MSPD evolved from the solid-phase extraction (SPE) technique, modified for application to solid and semi-solid matrices. 11 The MSPD procedure is based on the use of a sorbent, which acts as an abrasive in order to produce a modified "opening" of the solid matrix, facilitating the extraction process when using a suitable solvent for eluting the analytes. 12 The use of MSPD for pesticide recovery depends on the solubility of the pesticide in the eluting solvent, as well as the interactions between the matrix components, sorbent and eluent.…”

Section: Introductionmentioning

confidence: 99%

Multiclass MSPD method for pesticide determination in dehydrated Hyptis pectinata (sambacaitá) medicinal plant by GC-MS

Aquino

Souza

Maciel

et al. 2011

J. Braz. Chem. Soc.

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Um método baseado na técnica de dispersão da matriz em fase sólida foi desenvolvido para determinar resíduos de ametrina, tetraconazol, flumetralina, tebuconazol, pirimetanil, diclofuanida e cresoxim-metílico na planta medicinal desidratada Hyptis pectinata (sambacaitá) por cromatografia a gás acoplada a espectrometria de massas. Diferentes parâmetros foram avaliados, tais como: tipo (C 18 , alumina neutra, sílica gel e Florisil) e quantidades de sorvente e solvente de eluição (diclorometano, acetato de etila e diclorometano:acetato de etila (1:1, v/v)), sendo que o mais adequado foi o procedimento com 0,5 g de planta medicinal, 0,5 g de C 18 como sorvente e diclorometano (20 mL) como solvente de eluição. O método foi validado com amostras de planta medicinal fortificadas com agrotóxicos em diferentes níveis de concentração (0,05-1,0 μg g -1 ). Recuperações médias (n = 4) variaram de 83 a 127%, com coeficientes de variação entre 4 e 15%. Os limites de detecção (LOD) variaram entre 0,02 e 0,07 μg g -1 , enquanto que os limites de quantificação (LOQ), entre 0,05 e 0,1 μg g -1 .A method was developed using matrix solid-phase dispersion (MSPD), together with gas chromatography coupled to mass spectrometry (GC-MS) for determination of ametryn, tetraconazole, flumetralin, tebuconazole, pyrimethanil, dichlofluanid and kresoxim-methyl in dehydrated Hyptis pectinata (sambacaitá) medicinal plant material. The evaluated parameters included the type and amount of sorbent (C 18 , neutral alumina, silica gel and Florisil) and the nature of the eluent (dichloromethane, ethyl acetate and dichloromethane:ethyl acetate (1:1, v/v)). The best results were obtained using 0.5 g of plant material, 0.5 g of C 18 as sorbent and dichloromethane (20 mL) as the eluting solvent. The method was validated using plant samples spiked with pesticides at different concentration levels (0.05-1.0 μg g -1 ). Average recoveries (using four replicates) ranged from 83 to 127%, with relative standard deviations between 4 and 15%. Limits of detection (LOD) and quantification (LOQ) were in the ranges 0.02-0.07 μg g -1 and 0.05-0.1 μg g -1 , respectively.

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Matrix solid phase dispersion (MSPD)

Cited by 366 publications

References 195 publications

New Developments in Lycopene Analysis by Spectroscopic and Chromatographic Techniques, Accompanied With Mathematical Modelling

New Developments in Lycopene Analysis by Spectroscopic and Chromatographic Techniques, Accompanied With Mathematical Modelling

Selective separation of flavonoid glycosides in Dalbergia odorifera by matrix solid‐phase dispersion using titania

Multiclass MSPD method for pesticide determination in dehydrated Hyptis pectinata (sambacaitá) medicinal plant by GC-MS

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