Matriderm and Split Skin Grafting for Full-Thickness Pediatric Facial Burns

Jackson, Shane R.; Roman, Sandrine

doi:10.1093/jbcr/irz006

Cited by 20 publications

(17 citation statements)

References 5 publications

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“…Another option is the treatment with Matriderm ® , a single layer dermal substitute, which consists of a collagen-based matrix and allows a one-step procedure in combination with an autologous split-thickness skin graft as an alternative for the missing epidermal layer [96,97]. The use of Matriderm ® in the treatments of burns in aesthetic and functional important areas achieved good results.…”

Section: Dermal Substitutesmentioning

confidence: 99%

Historical Evolution of Skin Grafting—A Journey through Time

et al. 2021

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Autologous skin grafting was developed more than 3500 years ago. Several approaches and techniques have been discovered and established in burn care since then. Great achievements were made during the 19th and 20th century. Many of these techniques are still part of the surgical burn care. Today, autologous skin grafting is still considered to be the gold standard for burn wound coverage. The present paper gives an overview about the evolution of skin grafting and its usage in burn care nowadays.

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Section: Dermal Substitutesmentioning

confidence: 99%

Historical Evolution of Skin Grafting—A Journey through Time

et al. 2021

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“…199 Matriderm is not available in the United States and consists of native collagen scaffolding and elastin and has shown to be useful in facial burns. 200 Other covers are improving in quality and may become methods of permanent skin replacement, potentially avoiding temporary skin replacement and grafting altogether. 201,202 Examples include allogeneic engineered skin substitutes (ESSs), autologous composite cultured skin (CCS) and threedimensional (3D) bioprinting.…”

Section: Surgical Managementmentioning

confidence: 99%

A Critical Update of the Assessment and Acute Management of Patients with Severe Burns

Lang

Zhao²,

Kim

et al. 2019

Advances in Wound Care

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Burns are debilitating, life threatening, and difficult to assess and manage. Recent advances in assessment and management have occurred since a comprehensive review of the care of patients with severe burns was last published, which may influence research and clinical practice. Recent Advances: Recent advances have occurred in the understanding of burn pathophysiology, which has led to the identification of potential biomarkers of burn severity, such as protein C. There is new evidence about the potential superiority of natural colloids over crystalloids during fluid resuscitation, and new evidence about components of initial and perioperative management, including an improved understanding of pain following burns. Critical Issues: The limitations of the clinical examination highlight the need for imaging and biomarkers to assist in estimations of burn severity. Fluid resuscitation reduces mortality, although there is conjecture over the ideal method. The subsequent perioperative period is associated with significant morbidity and the evidence for preventing and treating pain, infection, and fluid overload while maximizing wound healing potential is described. Future Directions: Promising developments are ongoing in imaging technology, histopathology, biomarkers, and wound healing adjuncts such as hyperbaric oxygen therapy, topical negative pressure therapy, stem cell treatments, and skin substitutes. The greatest benefit from further research on management of patients with burns would most likely be derived from the elucidation of optimal fluid resuscitation protocols, pain management protocols, and surgical techniques from randomized controlled trials.

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“…Therefore, it is necessary to have objective information about the depth of the burn lesion, about the possibilities of the regenerative potential of cellular elements in the affected area [1, 6. The issues of reparative processes and angiogenesis in the engrafted autodermal graft also remain poorly understood and are the subject of heated debate. The problem of accelerating the regeneration processes in a burn wound, suppressing wound infection, improving the results of autodermoplasty remains unsolved [3]. Despite the fact that in recent years the arsenal of means and methods used for thermal injury has significantly expanded, the results of treatment are not always satisfactory [4].…”

Section: Active Surgical Treatment Optimization Of Severe Burns R E Lmentioning

confidence: 99%

“…The study design was approved by the FEFU Biomedicine School of Ethics. The size of biopsy specimens was 2-3 mm 3 . It was immunohistochemical identification of immunocompetent cells (Langerhans cells, macrophages, CD4, CD8).…”

Section: Ee Martynenko 12 Vv Usov 1 Tn Obidennikova 4 Gmentioning

confidence: 99%