Mathematical evaluation of plantaricin formation supports an auto-induced production mechanism

Klostermaier, P.; Scheyhing, Carsten H.; Ehrmann, Matthias A.; Vogel, Rudi F.

doi:10.1007/s002530051417

Cited by 9 publications

(4 citation statements)

References 30 publications

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“…acidification and growth. Maximum specific production has been registered mostly in the pH range 4.5e5.5, coinciding with what was reported by several authors (Calderón-Santoyo, Mendonza-García, García-Alvarado, & EscuderoAbarca, 2001;Klostermaier, Scheyhing, Ehrmann, & Vogel, 1999;Krier, Revol-Junelles, & Germain, 1998).…”

Section: Influence Of Nacl Concentration On Enterocin Productionsupporting

confidence: 84%

Antibacterial potential of Enterococcus faecium strains isolated from ewes’ milk and cheese

Rivas

Castro

Vallejo³

et al. 2012

LWT - Food Science and Technology

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Section: Influence Of Nacl Concentration On Enterocin Productionsupporting

confidence: 84%

Antibacterial potential of Enterococcus faecium strains isolated from ewes’ milk and cheese

Rivas

Castro

Vallejo³

et al. 2012

LWT - Food Science and Technology

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“…Plantaricin 423 activity also reached the highest titers when Lactobacillus plantarum 423 was grown in MRS medium supplemented with 1.7% (wt/ vol) bacteriological peptone (40). In contrast, the plantaricin production rate by L. plantarum TMW 1.25 was not affected by altering the nitrogen source of MRS medium (22).…”

Section: Discussionmentioning

confidence: 88%

Influence of Complex Nutrient Source on Growth of and Curvacin A Production by Sausage Isolate Lactobacillus curvatus LTH 1174

Verluyten

Leroy

Vuyst

2004

Appl Environ Microbiol

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) was used to fit the data describing growth and bacteriocin production. Both cell growth and bacteriocin activity were influenced by changes in the complex nutrient source concentration. Standard MRS medium clearly limited the growth of L. curvatus LTH 1174. Higher nutrient concentrations, up to a certain degree, led to improved growth, a higher attainable biomass concentration, and a higher bacteriocin activity in the supernatant. A lower concentration of complex nutrient source caused severe growth inhibition, leading to a lower biomass concentration but a much higher specific bacteriocin production. When examining the separate components of the complex nutrient source, a stimulating effect of bacteriological peptone on growth was found without an adverse effect on bacteriocin production, resulting in increased curvacin A activity. Furthermore, specific depletion of the amino acids tyrosine, serine, and asparagine/aspartic acid was observed for this strain.

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“…On the other hand, it was noticed that a too-poor environment is harmful for bacteriocin production by L. sakei CTC 494. In this matter, an increase of the yeast extract content of a tryptone medium increased the specific bacteriocin production by L. sakei CCUG 42687 (1), whereas alteration of the nitrogen source of MRS broth did not seem to affect the plantaricin production rate by Lactobacillus plantarum TMW1.25 (18). In view of practical applications, it seems to be of crucial importance that the bacteriocin-producing strain is perfectly adapted to the nutrient environment.…”

Section: Discussionmentioning

confidence: 99%

Growth of the Bacteriocin-Producing Lactobacillus sakei Strain CTC 494 in MRS Broth Is Strongly Reduced Due to Nutrient Exhaustion: a Nutrient Depletion Model for the Growth of Lactic Acid Bacteria

Leroy

Vuyst

2001

Appl Environ Microbiol

100

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Although commercial MRS broth has been designed to allow excellent growth of lactobacilli, most of these bacteria are still subjected to a self-inhibiting process. The most likely explanation is the accumulation of lactic acid or other toxic end products and the depletion of nutrients. In this study, the self-inhibition of Lactobacillus sakei CTC 494 was analyzed in a kinetic way, and a nutrient depletion model was set up to describe the growth inhibition process. This simple model has considerable advantages compared to commonly used descriptive models such as the logistic growth equation. It offers a better fit and a more realistic description of the growth data by taking into account both growth inhibition due to lactic acid production and changes in growth rates due to nutrient depletion. Depending on the fermentation conditions, in MRS broth there appears to be a strong decrease of the specific growth rate over time. Some undefined compounds present in the complex nitrogen source of MRS broth appear to be of crucial importance because of their limited availability. Moreover, nutrient availability affects bacteriocin production through its effect on cell growth as well as on the bacteriocin production per cell. A plateau value for the bacteriocin production by L. sakei CTC 494 was observed.

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Mathematical evaluation of plantaricin formation supports an auto-induced production mechanism

Cited by 9 publications

References 30 publications

Antibacterial potential of Enterococcus faecium strains isolated from ewes’ milk and cheese

Antibacterial potential of Enterococcus faecium strains isolated from ewes’ milk and cheese

Influence of Complex Nutrient Source on Growth of and Curvacin A Production by Sausage Isolate Lactobacillus curvatus LTH 1174

Growth of the Bacteriocin-Producing Lactobacillus sakei Strain CTC 494 in MRS Broth Is Strongly Reduced Due to Nutrient Exhaustion: a Nutrient Depletion Model for the Growth of Lactic Acid Bacteria

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