Maternity in Newcastle Upon Tyne a Community Study

Russell, J. K.; Fairweather, D. V. I.; Millar, David; Brown, Alexander; Pearson, Rachel; Neligan, G. A.; Anderson, G.S.

doi:10.1016/s0140-6736(63)91464-8

Cited by 24 publications

(7 citation statements)

References 6 publications

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“…If the mother was uncertain of her menstrual dates or if these differed from an early ultrasound assessment (<20 weeks) by more than 14 days, the ultrasound estimate was then recorded. For 1960–75 the distribution by gestational age of singleton live births to Newcastle residents in the study area was available from the Newcastle Maternity Survey 19 and unpublished work of the late Professor David Miller. As the distribution by gestational age is almost identical in the 1960–75 and the 1984–94 cohorts, we have assumed this distribution also holds for the intervening years 1976–83.…”

Section: Methodsmentioning

confidence: 99%

Analysis by gestational age of cerebral palsy in singleton births in north‐east England 1970–94

Drummond

Colver

2002

Paediatric Perinatal Epid

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Summary We report from a well‐established cerebral palsy (CP) register the changes in CP rates by gestational age for singleton births over a 25‐year period in north‐east England. The gestational ages of numerators and denominators are of high accuracy back to 1970 because academic units in paediatrics and obstetrics were studying the assessment of gestational age in individual infants, and the distribution of gestational age across all births in the north‐east from the 1960s. The rate of CP rose between 1970–75 and 1990–94 from 1.6 to 2.3 per 1000 singleton neonatal survivors, a rise of 0.7/1000 [95% CI 0.2, 1.3]. There was little change in the rate of CP in term infants whereas in preterm infants (<37 weeks) it rose from 5.5 to 16.8, a rise of 11.3/1000 [95% CI 5.9, 16.8]. Rises occurred in the three preterm gestational age bands <28, 28–31, 32–36 weeks with the most marked rise in those <28 weeks from 0 to 112.7. The proportion of all cases of CP arising in the preterm group rose from 19% to 45%; and the proportion of the severest cases arising in the preterm group rose from 8% to 55%. In those born after 32 weeks, there is a preponderance of small‐for‐gestation infants, with 10% more than two standard deviations below the mean. All types of CP are more common in infants below average weight for gestation and this is most marked for the non‐spastic types that are almost only seen in term, small‐for‐gestation infants. Gestational age is the crucial determinant of rate of CP and the increase in prevalence seen over the past 25 years is due to increased rates in preterm infants, not term infants. Both conclusions, suspected from birthweight analyses, are now demonstrated conclusively, with the contribution coming from those 32–36 weeks gestation as well as very preterm infants.

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Section: Methodsmentioning

confidence: 99%

Analysis by gestational age of cerebral palsy in singleton births in north‐east England 1970–94

Drummond

Colver

2002

Paediatric Perinatal Epid

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“…In addition, an attempt was made to quantify the environment in which they had been reared. Social class based upon the occupation of the father had been recorded at birth in the Newcastle Maternity Survey (Russell et al, 1963). Further information was collected from a number of sources.…”

Section: Methodsmentioning

confidence: 99%

The normal short child: Community study of children in Newcastle upon Tyne

Lacey¹,

Parkin²

1974

Archives of Disease in Childhood

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“…6 The availability of accurate population-based gestational age is one of the leading strengths. Newcastle clinicians have a long history of interest in obstetric epidemiology [38][39][40] supported by the Medical Research Council Reproduction and Growth Unit which was housed in one of the two Newcastle maternity hospitals from 1965. As a result, gestational age was assessed by both obstetricians and paediatricians with great care.…”

Section: Data Strengths and Limitationsmentioning

confidence: 99%

Stillbirth and infant mortality in singletons by cause of death, birthweight, gestational age and birthweight-for-gestation, Newcastle upon Tyne 1961-2000

Glinianaia

Rankin

Pearce

et al. 2010

Paediatric and Perinatal Epidemiology

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The dramatic reduction observed in stillbirth and infant mortality over the last few decades has not been assessed by both birthweight and gestation. We have explored temporal changes in stillbirth and infant mortality in Newcastle upon Tyne, UK, by cause of death, birthweight, gestational age, birthweight standardised for gestation and infant sex during 1961-2000. We included 131 044 singleton births to mothers resident in Newcastle, including 1342 stillbirths and 1620 infant deaths. Cause-, birthweight-, gestational age- and birthweight-for-gestation-specific stillbirth (per 1000 total births) and infant mortality (per 1000 livebirths) rates were compared between 1961-80 and 1981-2000 and between individual consecutive decades. Between 1961 and 2000, total stillbirth and infant mortality rates declined dramatically from 23.4 to 4.7 per 1000 total births and from 25.7 to 5.9 per 1000 livebirths, respectively. Rates fell continuously during the first two study decades; however, from 1981-90 to 1991-2000 the decline was not statistically significant. Between 1961-80 and 1981-2000, both stillbirth and infant mortality significantly declined in all birthweight and gestational age categories and for most leading causes of death. Although the population mean birthweight during 1981-2000 [3304 g (SD +/- 569)] was significantly higher than during 1961-80 [3255 g (SD +/- 572)] (P < 0.0001), the lowest stillbirth and infant mortality rates in 1981-2000 were consistently at about 1 SD above the mean birthweight, with mortality rates increasing for babies with lower or higher weight-for-gestation. Declines in stillbirth and infant mortality in Newcastle were associated with reductions in birthweight- and gestational age-specific mortality rates and occurred in most cause-specific groups of death.

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Maternity in Newcastle Upon Tyne a Community Study

Cited by 24 publications

References 6 publications

Analysis by gestational age of cerebral palsy in singleton births in north‐east England 1970–94

Analysis by gestational age of cerebral palsy in singleton births in north‐east England 1970–94

The normal short child: Community study of children in Newcastle upon Tyne

Stillbirth and infant mortality in singletons by cause of death, birthweight, gestational age and birthweight-for-gestation, Newcastle upon Tyne 1961-2000

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