Maternal Serum Hpl Levels in Normal and Complicated Pregnancy as an Index of Placental Function

Placental Protein 5 (Pp5) in Complicated Pregnancies

“…The placental proteins, SPI and hPL, have been shown to be of some use in the detection of intrauterine growth retardation (Ylikorkala, 1973;Gordon et al, 1977;Towler et al, 1977). It was therefore somewhat surprising that serum PP5 concentrations in pregnancies associated with fetal growth retardation were indistinguishable from normal values, especially in view of the observation (reported in the preceding paper) of a correlation between PP5 concentration and fetal birth weight, albeit at a level slightly below that required for conventional significance.…”

Maternal blood levels of human placental lactogen in the prediction of fetal growth retardation: choosing a cut‐off point between normal and abnormal

“…Levels of human placental lactogen (hPL) in maternal blood have been used for many years in the prediction of fetal wellbeing and growth retardation (Saxena et al 1969;Varma et al 1971;Lindberg & Nilsson 1973;Ylikorkala 1973;England et al 1974;Edwards et al 1976; 0306-5456/83/0600-05 1 1%02.00 0 1983 British Journal of Obstetrics and Gynaecology Letchworth 1976;Hensleigh et al 1977;Gordon ef al. 1978).…”

Role of Nucleic Acids in the Regulation of Human Placental Lactogen Synthesis

“…Similarly, it has not been possible to demonstrate an effect of insulin, progesterone, cortisone, estriol and various other steroids, prostaglandins, oxytocin, cyclic AMP or thyroid stimulating hormone [24, 27, 34, 43, 50b, 59]. Some evidence indicates that glucose loading can depress hPL levels [49] although other reports suggest no relationship between blood glucose and hPL [43,44,54,59]. Glycerol, yS-hydroxybutyrate and free fatty acid concentrations are not re lated to hPL concentrations [20,43].…”