Maternal methyl-enriched diet in rat reduced the audiogenic seizure proneness in progeny

The Krushinsky-Molodkina rat strain: The study of audiogenic epilepsy for 65 years

“…4. Excitatory amino acids in the KM rat strain medulla -the background levels (white columns), and in the AS stage of maximal tonic seizures (black columns) (modified from [54]). Ordinate -the percentage of amino acid content in relation to 100% (intact Wistar rat level): 1 -aspartate, 2 -glutamate, 3 -GABA, 4 -glycine, 5 -taurine.…”

“…Another new aspect of interference into brain ontogeny was performed recently in the study of DNA methylation [54]. Audiogenic epilepsy proneness was analyzed in the progeny of rats from two strains (audiogenic seizure-prone strain "4" and audiogenic seizure-nonprone strain "0").…”

Common data elements (CDEs) for preclinical epilepsy research: Introduction to CDEs and description of core CDEs. A TASK3 report of the ILAE/AES joint translational task force

“…Several studies have shown that the composition of the diet can affect seizures . Although the most common example is the ketogenic diet, other diets have also been shown to affect rodents .…”

“…Several studies have shown that the composition of the diet can affect seizures. 43,44 Although the most common example is the ketogenic diet, other diets have also been shown to affect rodents. 43,44 For females, the degree that phytoestrogens are included in the diet is very important because it has been shown to exert an influence on the brain and behavior.…”

“…43,44 Although the most common example is the ketogenic diet, other diets have also been shown to affect rodents. 43,44 For females, the degree that phytoestrogens are included in the diet is very important because it has been shown to exert an influence on the brain and behavior. 45 Furthermore, dietary nutritional supplementation can influence aspects of breeding including litter sizes.…”