Maternal exposures to fine and ultrafine particles and the risk of preterm birth from a retrospective study in Beijing, China

Fang, Jugao; Yang, Ying; Zou, Xiaoxuan; Xu, Hongbing; Wang, Shuo; Wu, Ruihong; Jia, Jiajing; Xie, Yunfei; Yang, Huajun; Yuan, Ningman; Hu, Meina; Deng, Yuzhi; Zhao, Yanqing; Wang, Tong; Zhu, Yu; Ma, Xu; Fan, Meng; Wu, Jianbin; Song, Xiaoming; Huang, Wei

doi:10.1016/j.scitotenv.2021.151488

Cited by 6 publications

(1 citation statement)

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“…Bové et al reported that BC could pass through the placenta and accumulate on the fetal side of the placenta, which may represent a potential mechanism that leads to the occurrence of preterm birth (31). Previous studies conducted among singletons also reported significant associations between prenatal BC exposure and an increased risk of preterm birth (28,32,33). In this study, the associations of prenatal BC exposure with PTB risk were marginally significant, with an OR of 1.40 (95% CI, 0.99, 2.00).…”

Section: Figurementioning

confidence: 99%

Prenatal exposure to fine particulate matter and the risk of spontaneous preterm birth: A population-based cohort study of twins

Qiao

Fan²,

Bao³

et al. 2022

Front. Public Health

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BackgroundStudies in singletons have suggested that prenatal exposure to fine particulate matter (PM2.5) and some of its chemical components is associated with an increased risk of preterm birth (PTB). However, no study has been conducted in twins.PurposeTo examine the associations of maternal exposure to total PM2.5 mass and its carbonaceous components with PTB in twin pregnancies.MethodsA total of 1,515 pairs of twins and their mothers were enrolled from a previous twin birth cohort that had been conducted at the Shanghai First Maternity and Infant Hospital School of Medicine of Tongji University in China. Participants who had iatrogenic PTBs were excluded. Maternal exposure to total PM2.5 mass and two carbonaceous components, namely, organic carbon (OC) and black carbon (BC), was estimated by a satellite-based model. The associations between PM2.5 exposure and the risk of spontaneous PTB were evaluated by logistic regression analysis.ResultsThis study found that exposure to total PM2.5 mass and OC during the second trimester of pregnancy was significantly associated with an increased risk of spontaneous PTB. An interquartile range (IQR) increase in total PM2.5 mass and OC exposure during the second trimester was associated with 48% (OR = 1.48, 95% CI, 1.06, 2.05) and 50% (OR = 1.50, 95% CI, 1.00, 2.25) increases in the odds of PTB, respectively. However, no significant association was found between BC exposure during any exposure window and the risk of PTB.ConclusionThe findings suggest that exposure to ambient air pollution with fine particles may be a risk factor for spontaneous PTB in twin pregnancies. The middle stage of pregnancy seems to be a critical window for the impacts of PM2.5 exposure on PTB in twin pregnancies.

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Section: Figurementioning

confidence: 99%