Maternal exposures and risk of oral clefts in South Vietnam

Dien, Vu Hoa Anh; McKinney, Christy M.; Pisek, Araya; Pitiphat, Waranuch

doi:10.1002/bdr2.1192

Cited by 23 publications

(38 citation statements)

References 46 publications

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“…13 Growing scientific evidence indicating that the advanced maternal age is a factor associated with the development of congenital anomalies. 16,20 This is due to the aging of the ovules, which may have structural defects due to advanced age. 16,20 Another factor influencer are the pre-existing chronic diseases, which may weaken the proper functioning of the female body, causing damage to the fetus.…”

Section: Discussionmentioning

confidence: 99%

“…16,20 This is due to the aging of the ovules, which may have structural defects due to advanced age. 16,20 Another factor influencer are the pre-existing chronic diseases, which may weaken the proper functioning of the female body, causing damage to the fetus. 16,20 However, paradoxically, we found a case-control study conducted with 340 babies in Vietnam, which pointed out as the age group most affected, the population aged up to 24 years old.…”

Section: Discussionmentioning

confidence: 99%

“…16,20 Another factor influencer are the pre-existing chronic diseases, which may weaken the proper functioning of the female body, causing damage to the fetus. 16,20 However, paradoxically, we found a case-control study conducted with 340 babies in Vietnam, which pointed out as the age group most affected, the population aged up to 24 years old. 21 In Argentina, a casecontrol study with 13,444 babies also showed that women aged less than 19 had more chances of presenting children with cleft lip and/or cleft palate.…”

Section: Discussionmentioning

confidence: 99%

“…21 With respect to the presence of a companion, this study indicated that the absence of a partner is associated with cleft lip and/or cleft palate, thus ratifying, findings from other studies. [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] Another factor-associated care to children with cleft lip and/or cleft palate is the insufficient number of prenatal consultations, lower than the recommended minimum of seven. The quality and quantity of pre-natal consultations are essential for maternal and child safety, as they are linked directly with the rates of neonatal death.…”

Section: Discussionmentioning

confidence: 99%

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Factors associated with the presence of cleft lip and / or cleft palate in Brazilian newborns

Shibukawa

Rissi

Higarashi

et al. 2019

Rev. Bras. Saude Mater. Infant.

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Objectives: to analyze the trend and the associated factors with the presence of cleft lip and/or cleft palate in Brazilian newborns, in order to verify possible associations with maternal care and newborn factors. Methods: a cross-sectional and ecological study, involving all live births in Brazil, recorded in the Information System on Live Births from 2005 to 2016. Maternal and infant information were evaluated using trend analysis and odds ratio, with a 95% confidence interval. The analyses were performed using SPSS software. Results: we analyzed 17,800 live births with presence of cleft lip and/or cleft palate. The Brazilian prevalence rate was 0.51 / 1000 live births, with South and Southeast Regions registering higher rates than the national rate. There was an association with maternal age above 35 years old, with no partner, less than seven prenatal consultations, premature birth and cesarean section. About the factors of the newborn, being male, Apgar less than seven in the 1st and 5th minutes of life, low birth weight and white color were associated. Conclusions: Brazil has an increasing tendency for cleft lip and/or cleft palate (p=0.019), reinforcing the need to strengthen health care networks, providing adequate support for newborn with cleft lip and/or cleft palate and their families.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Factors associated with the presence of cleft lip and / or cleft palate in Brazilian newborns

Shibukawa

Rissi

Higarashi

et al. 2019

Rev. Bras. Saude Mater. Infant.

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“…En el desarrollo normal, el paladar secundario se ha completado la fusión con el labio y el tabique nasal por la décima semana del desarrollo embrionario 11 . Al estar las fisuras de labio y paladar asociadas con niveles variables de deformidad y disfunción, implican la deficiencia ósea, de mucosa y de los músculos 12 ,ocasionando problemas con la alimentación, el habla, la audición e integración social, disminuyendo la calidad de vida de quien la padece 13 .…”

Section: Introductionunclassified

Factores de riesgo asociados a fisuras no sindrómicas de labio y paladar en neonatos del Instituto Nacional Materno Perinatal, 2012 -2017

Huaynate-Villalobos¹,

Munayco-Magallanes²

2019

Investigación Materno Perinatal

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Objetivo. Determinar los factores de riesgo asociados a fisuras no sindrómicas de labio y paladar en neonatos del Instituto Nacional Materno Perinatal, durante el 2012 al 2017. Material y método. Estudio observacional, analítico, transversal y retrospectivo, en el que se evaluó historias clínicas de madres y neonatos, se registraron dos grupos; un grupo de casos conformado por 40 neonatos con fisuras no sindrómicas de labio y paladar y, un grupo control formado por 52 neonatos sanos. Resultados. Se encontró mayor presencia de fisuras no sindrómicas de labio y paladar en neonatos de sexo masculino (22,8%), dándose más en el año 2016, y el diagnóstico más frecuente fue fisura del paladar duro y del paladar blando con labio leporino bilateral (Q37.4) (19,6%). Además, se encontró que el presentar antecedentes aumenta ligeramente el riesgo de nacer con fisuras no sindrómicas de labio y paladar, y las gestantes que presentan edad materna de alto riesgo y no consumen ácido fólico tienen 1,228 y 4,891 más riesgo de desarrollar un bebé con fisuras de labio y paladar respectivamente. Conclusiones. Las fisuras de labio y paladar, se presentaron en mayor frecuencia en neonatos de sexo masculino, en el año 2016 y el diagnóstico de fisura de labio y paladar más frecuente el Q37.4, y los factores de riesgo asociados a fisuras no sindrómicas de labio y paladar fueron la edad materna y el no consumo de ácido fólico.

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Maternal dietary caffeine consumption and risk of birth defects in the National Birth Defects Prevention Study, 1997–2011

Williford

Howley

Fisher

et al. 2023

Birth Defects Research

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Background: Caffeine consumption is common during pregnancy, but published associations with birth defects are mixed. We updated estimates of associations between prepregnancy caffeine consumption and 48 specific birth defects from the National Birth Defects Prevention Study (NBDPS) for deliveries from 1997 to 2011.Methods: NBDPS was a large population-based case-control study conducted in 10 U.S. states. We categorized self-reported total dietary caffeine consumption (mg/day) from coffee, tea, soda, and chocolate as: <10, 10 to <100, 100 to <200, 200 to <300, and ≥ 300. We used logistic regression to estimate adjusted odds ratios (aORs [95% confidence intervals]). Analyses for defects with ≥5 exposed case children were adjusted for maternal race/ethnicity, age at delivery, body mass index, early pregnancy cigarette smoking and alcohol use, and study site. Results: Our analysis included 30,285 case and 11,502 control children, with mothers of 52% and 54%, respectively, reporting consuming <100 mg caffeine, and 11% of mothers of both cases and controls reported consuming ≥300 mg per day. Low (10 to <100 mg/day) levels of prepregnancy caffeine consumption were associated with statistically significant increases in aORs (1.2-1.7) for 10 defects. Associations with high (≥300 mg/day) levels of caffeine were generally weaker, except for craniosynostosis and aortic stenosis (aORsConclusions: Given the large number of estimates generated, some of the statistically significant results may be due to chance and thus the weakly increased aORs should be interpreted cautiously. This study supports previous observations suggesting lack of evidence for meaningful associations between caffeine consumption and the studied birth defects.

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Maternal exposures and risk of oral clefts in South Vietnam

Cited by 23 publications

References 46 publications

Factors associated with the presence of cleft lip and / or cleft palate in Brazilian newborns

Factors associated with the presence of cleft lip and / or cleft palate in Brazilian newborns

Factores de riesgo asociados a fisuras no sindrómicas de labio y paladar en neonatos del Instituto Nacional Materno Perinatal, 2012 -2017

Maternal dietary caffeine consumption and risk of birth defects in the National Birth Defects Prevention Study, 1997–2011

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