Maternal Complications Associated with Severe Preeclampsia

Abstract

Objective Hypertension disorders are associated with higher rates of maternal, fetal, and infant mortality, and severe morbidity, especially in cases of severe preeclampsia, eclampsia, and HELLP syndrome. The aim of the study was to determine maternal outcomes in pregnant women with severe preeclampsia. Data Source The data source consisted of 349 cases with severe preeclampsia. Design A cross-sectional study was undertaken on 349 cases of severe preeclampsia in pregnancy. Setting/Period The patients selected for this study were from those who presented at Kermanshah University of Medical Sciences, Department of Obstetrics and Gynecology during [2007][2008][2009]. Materials and Methods Statistical analysis was performed using SPSS 16 software and conducting Chi square and independent sample t tests. Demographic data involving age, parity, gestational age, clinical, and laboratory findings were recorded from the medical files. In addition, delivery route, indications of cesarean delivery, and maternal complications were determined. Results Of the 349 severely preeclampsia cases, among the 22 cases (6.3 %) who had suffered from eclamptic seizers, 17 cases (77.3 %) were in the age group of 18-35 years (P = 0.351) and 13 cases (59.1 %) in the gestational age group of 28-37 weeks (P = 0.112). One case (0.3 %) was demonstrated to have HELLP syndrome. Placental abruption was obstetric complication in 7.7 % (27 cases). Delivery route was vaginal in 120 cases (34.4 %), while 229 cases (65.6 %) underwent cesarean delivery. The most frequent maternal complication (37 cases) reported was coagulopathy (10.6 %). Conclusions We concluded that severe preeclampsia and eclampsia are associated with higher rates of maternal severe morbidity and that these two factors still remain the major contributors to maternal morbidity in Iran.

Maternal and Perinatal Complications of Severe Preeclampsia

“…All these findings were in agreement with Mohammad Ahadi et al (2015). [10] Visual disturbances were seen in 3.8%, as in Nankali et al (2013). [12] In the present study the incidence of pulmonary oedema is very high (29.3%) as compared to literature, because most patients come at a late stage to our Institution as referred cases.…”

Study of Nitrosative Stress in ‘Pregnancy Induced Hypertension’

“…About 5% females with pre-eclampsia develop eclampsia and of these 15% die from PIH itself or its complications. Severe maternal complications include eclamptic seizures, intracerebral haemorrhage, pulmonary oedema due to capillary leak, myocardial dysfunction, acute renal failure due to vasospasm, hepatic damage [4]. PIH is associated with various complications which can lead to foetal mortality.…”

Validation of fullPIERS model for prediction of adverse outcomes among women with severe pre‐eclampsia

“…Pre‐eclampsia is characterized by an increase in blood pressure after the 20th week of pregnancy together with proteinuria, maternal organ dysfunction, and/or uteroplacental insufficiency . It is associated with high maternal morbidity and mortality and increases the risk of adverse perinatal outcomes …”

“…4 It is associated with high maternal morbidity and mortality and increases the risk of adverse perinatal outcomes. [5][6][7][8][9][10][11] Definitive treatment for pre-eclampsia is the delivery of the fetus.…”