Maternal Alcohol Consumption before and during Pregnancy and the Risks of Congenital Heart Defects in Offspring: A Systematic Review and Meta-analysis

Sun, Jian; Chen, Xiaoling; Chen, Huajun; Ma, Zhengliang; Zhou, Jianwei

doi:10.1111/chd.12271

Cited by 22 publications

(25 citation statements)

References 46 publications

(75 reference statements)

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“…Therefore, it is worthwhile that a meta-analysis by Wen et al [ 19 ] found no association between maternal alcohol consumption during pregnancy and the risk of CHDs. These findings confirmed conclusions of a previous systematic review [ 20 ]. The major cause of acquired heart disease in developed countries is represented by coronary artery abnormalities, that is the main complication of KD.…”

Section: Reviewsupporting

confidence: 92%

Advances in paediatrics in 2016: current practices and challenges in allergy, autoimmune diseases, cardiology, endocrinology, gastroenterology, infectious diseases, neonatology, nephrology, neurology, nutrition, pulmonology

et al. 2017

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This review reports main progresses in various pediatric issues published in Italian Journal of Pediatrics and in international journals in 2016. New insights in clinical features or complications of several disorders may be useful for our better understanding. They comprise severe asthma, changing features of lupus erythematosus from birth to adolescence, celiac disease, functional gastrointestinal disorders, Moebius syndrome, recurrent pneumonia. Risk factors for congenital heart defects, Kawasaki disease have been widely investigated. New diagnostic tools are available for ascertaining brucellosis, celiac disease and viral infections. The usefulness of aCGH as first-tier test is confirmed in patients with neurodevelopmental disorders. Novel information have been provided on the safety of milk for infants. Recent advances in the treatment of common disorders, including neonatal respiratory distress syndrome, hypo-glycemia in newborns, atopic dermatitis, constipation, cyclic vomiting syndrome, nephrotic syndrome, diabetes mellitus, regurgitation, short stature, secretions in children with cerebral palsy have been reported. Antipyretics treatment has been updated by national guidelines and studies have excluded side effects (e.g. asthma risk during acetaminophen therapy). Vaccinations are a painful event and several options are reported to prevent this pain. Adverse effects due to metabolic abnormalities are reported for second generation antipsychotic drugs.

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Section: Reviewsupporting

confidence: 92%

Advances in paediatrics in 2016: current practices and challenges in allergy, autoimmune diseases, cardiology, endocrinology, gastroenterology, infectious diseases, neonatology, nephrology, neurology, nutrition, pulmonology

et al. 2017

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“…Congenital heart defects (CHDs) are groups of congenital cardiovascular disorders or diseases that affect about 1% of live births worldwide [1][2][3]; also, it is the leading cause of infant deaths [4]. Based on the data from American Heart Association, there are over 20 common types of CHDs that can be observed in clinic, including but not limited to atrial septal defect (ASD), tetralogy of Fallot (TOF), and conotruncal heart defect (CTD) [5].…”

Section: Introductionmentioning

confidence: 99%

Is maternal smoking during pregnancy associated with an increased risk of congenital heart defects among offspring? A systematic review and meta-analysis of observational studies

Zhang

Cui

Zhang³

et al. 2016

The Journal of Maternal-Fetal & Neonatal Medicine

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“…Fetal echocardiography in these cases is only indicated if the results of a detailed fetal ultrasound examination ( Current Procedural Terminology code 76811) are abnormal . These conditions include: Gestational diabetes diagnosed after the second trimester Warfarin exposure Alcohol exposure Echogenic intracardiac focus Maternal fever or viral infection with seroconversion only Isolated CHD in a relative further removed from second degree to the fetus …”

Section: Indicationsmentioning

confidence: 99%

AIUM Practice Parameter for the Performance of Fetal Echocardiography

2019

J of Ultrasound Medicine

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Maternal Alcohol Consumption before and during Pregnancy and the Risks of Congenital Heart Defects in Offspring: A Systematic Review and Meta-analysis

Abstract: In summary, this meta-analysis provided no positive association between maternal alcohol consumption and risk of CHDs.

Cited by 22 publications

References 46 publications

Advances in paediatrics in 2016: current practices and challenges in allergy, autoimmune diseases, cardiology, endocrinology, gastroenterology, infectious diseases, neonatology, nephrology, neurology, nutrition, pulmonology

Advances in paediatrics in 2016: current practices and challenges in allergy, autoimmune diseases, cardiology, endocrinology, gastroenterology, infectious diseases, neonatology, nephrology, neurology, nutrition, pulmonology

Is maternal smoking during pregnancy associated with an increased risk of congenital heart defects among offspring? A systematic review and meta-analysis of observational studies

AIUM Practice Parameter for the Performance of Fetal Echocardiography

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