Materials and Methods in Chemical‐Sensor Manufacturing

Bănică, Florinel‐Gabriel

doi:10.1002/9781118354162.ch5

Chemical Sensors and Biosensors 2012

DOI: 10.1002/9781118354162.ch5

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Materials and Methods in Chemical‐Sensor Manufacturing

Florinel‐Gabriel Bănică

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2015

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SPR-Based Affinity Biosensors as Innovative Analytical Devices

Scarano

Mariani

Minunni

2015

J. Lightwave Technol.

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Surface Plasmon Resonance affinity biosensors and the new technology named SPR imaging are successful analytical devices that represent useful and versatile analytical tools for a variety of applications in bioanalytical chemistry. The selectivity of these systems rely mainly on the bioreceptor immobilized on the biochip surface, which can range from nucleic acid sequence to antibodies, proteins, and new synthetic bioreceptors. Thank to SPR imaging (SPRi), the parallel immobilization of tens bioreceptors allows the multi-analyte detection in real time and label free manner. Moreover, different assay designs can be tailored for a broad range of different molecular weight target analytes, from small molecules (hundreds of Da) to living cells. In this chapter we will focus on examples relative to SPR-based affinity biosensors developed for medicine applications.0733-8724 (c) Journal of Lightwave Technology b) SPRi results obtained for each spot of the array by comparing the three signal sampling methods (B-D) displayed up). SDs are the average calculated on the total number of the selected ROIs for each considered method, and for 3 ppm hIgG injections in replicates (n = 3). With

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SPR-Based Affinity Biosensors as Innovative Analytical Devices

Scarano

Mariani

Minunni

2015

J. Lightwave Technol.

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Materials and Methods in Chemical‐Sensor Manufacturing

Cited by 1 publication

References 90 publications

SPR-Based Affinity Biosensors as Innovative Analytical Devices

SPR-Based Affinity Biosensors as Innovative Analytical Devices

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