Material Properties of Inorganic Bovine Cancellous Bovine: Nukbone

Pina, Cristina Della; Palma, B.; Munguía, Nadia

doi:10.1063/1.2356454

Cited by 2 publications

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“…Moreover, Mg 2+ ions stimulate cellular adhesion to biomaterial surfaces and new bone formation. , Previous results have shown that HAp doped with Mg 2+ and Mg 2+ together with CO 3 2– improved the behavior of MSC and MG-63 cells regarding adhesion, proliferation, and metabolic activation compared to the stoichiometric one . On the other hand, the economic and environmental implications of HAp extracted from a biological source have increased its use for bone graft, as well as for coatings of metallic implants, among other biomedical applications. − …”

Section: Introductionmentioning

confidence: 99%

Preferred Growth Orientation of Apatite Crystals on Biological Hydroxyapatite Enriched with Bioactive Glass: A Biomimetic Behavior

Rincón-López

Hermann-Muñoz

Cinca-Luis

et al. 2019

Crystal Growth & Design

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The morphological, structural and chemical transformations during the biomineralization process associated with the apatite formation from bovine-derived hydroxyapatite (BHAp) and BHAp/Nagelschmidtite composite obtained from the mixture of BHAp and Vitryxx® bioactive glass are here presented. The study is focused on the structural characteristics of apatite formation and maturation process taking place at the biomaterial surface. The use of a biological HAp is of interest aiming to mimic the natural process of bone mineral matrix formation in the crystallization mechanism. This process was characterized by transmission electron microscopy (TEM), where the initial stage was identified as the formation of a hydrated amorphous matrix followed by the appearance of randomly oriented nanocrystals that later coalesce and grow with preferred orientation to c-axis. This behavior is a biomimetic process based on the alignment of natural bone apatite along collagen fibrils. The understanding of natural processes of mineral matrix formation at micro and nanoscale levels on bioactive materials is of great interest to address the effect of size, structure, and composition of apatite nanocrystals on the biologic phenomena involved in osseointegration.

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Section: Introductionmentioning

confidence: 99%

Preferred Growth Orientation of Apatite Crystals on Biological Hydroxyapatite Enriched with Bioactive Glass: A Biomimetic Behavior

Rincón-López

Hermann-Muñoz

Cinca-Luis

et al. 2019

Crystal Growth & Design

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Pore cross-section area on predicting elastic properties of trabecular bovine bone for human implants

Maciel

Presbítero

Pina

et al. 2015

Bio-Medical Materials and Engineering

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A clear understanding of the dependence of mechanical properties of bone remains a task not fully achieved. In order to estimate the mechanical properties in bones for implants, pore cross-section area, calcium content, and apparent density were measured in trabecular bone samples for human implants. Samples of fresh and defatted bone tissue, extracted from one year old bovines, were cut in longitudinal and transversal orientation of the trabeculae. Pore cross-section area was measured with an image analyzer. Compression tests were conducted into rectangular prisms. Elastic modulus presents a linear tendency as a function of pore cross-section area, calcium content and apparent density regardless of the trabecular orientation. The best variable to estimate elastic modulus of trabecular bone for implants was pore cross-section area, and affirmations to consider Nukbone process appropriated for marrow extraction in trabecular bone for implantation purposes are proposed, according to bone mechanical properties. Considering stress-strain curves, defatted bone is stiffer than fresh bone. Number of pores against pore cross-section area present an exponential decay, consistent for all the samples. These graphs also are useful to predict elastic properties of trabecular samples of young bovines for implants.

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Material Properties of Inorganic Bovine Cancellous Bovine: Nukbone

Cited by 2 publications

References 0 publications

Preferred Growth Orientation of Apatite Crystals on Biological Hydroxyapatite Enriched with Bioactive Glass: A Biomimetic Behavior

Preferred Growth Orientation of Apatite Crystals on Biological Hydroxyapatite Enriched with Bioactive Glass: A Biomimetic Behavior

Pore cross-section area on predicting elastic properties of trabecular bovine bone for human implants

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