Massive Bleeding Due to Acute Hemorrhagic Gastritis

Lulu, Donald J.; Dragstedt, Lester R.

doi:10.1001/archsurg.1970.01340290006002

Cited by 37 publications

(17 citation statements)

References 7 publications

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“…[1][2][3] It rapidly penetrates the gastric mucosa, causing membrane damage, exfoliation of cells, and erosions. The subsequent increase in mucosal permeability together with the release of vasoactive products from mast cells, macrophages, and other blood cells can lead to vascular injury, necrosis, and ulcer formation.…”

Section: Discussionmentioning

confidence: 99%

“…Jeong-Hwan KIM, 1 Seok-Keun CHOI, 1 Sang-Yun CHOI, 1 Han-Kyeom KIM, 2 and Hyo-Ihl CHANG Ethanol is known to produce erosions, ulcerative lesions, and petechial bleeding in the mucosa of the stomach in humans. [1][2][3] Oral administration of ethanol to rats rapidly induces gastric mucosal lesions, which are commonly used to study both the pathogenesis of and therapy for human ulcerative disease.…”

Section: Suppressive Effect Of Astaxanthin Isolated From the Xanthophmentioning

confidence: 99%

“…[1][2][3] Oral administration of ethanol to rats rapidly induces gastric mucosal lesions, which are commonly used to study both the pathogenesis of and therapy for human ulcerative disease. Ethanol rapidly penetrates the gastric mucosa, and it causes membrane damage, exfoliation of cells, erosion, and ulcer formation.…”

Section: Suppressive Effect Of Astaxanthin Isolated From the Xanthophmentioning

confidence: 99%

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Suppressive Effect of Astaxanthin Isolated from theXanthophyllomyces dendrorhousMutant on Ethanol-Induced Gastric Mucosal Injury in Rats

Kim¹,

Choi²,

Choi³

et al. 2005

Bioscience, Biotechnology, and Biochemistry

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Section: Discussionmentioning

confidence: 99%

Section: Suppressive Effect Of Astaxanthin Isolated From the Xanthophmentioning

confidence: 99%

Section: Suppressive Effect Of Astaxanthin Isolated From the Xanthophmentioning

confidence: 99%

See 1 more Smart Citation

Suppressive Effect of Astaxanthin Isolated from theXanthophyllomyces dendrorhousMutant on Ethanol-Induced Gastric Mucosal Injury in Rats

Kim¹,

Choi²,

Choi³

et al. 2005

Bioscience, Biotechnology, and Biochemistry

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“…In emergency operations, however, the mortality is considerably higher than in elective surgery. Older patients with haemorrhagic gastritis especially have a high mortality in emergency surgery (9).…”

Section: Introductionmentioning

confidence: 99%

Propantheline Bromide in Massive Upper Gastrointestinal Haemorrhage

Rimsten

Wiklund

Krause

1975

Upsala Journal of Medical Sciences

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The effectiveness of the anticholinenergic, propantheline bromide, administered parenterally in patients with upper gastrwintestinal bleeding has been investigated in a double-blind study. The basic material consisted of 99 patients. No differences were found between the group receiving propantbeline bromide and the group receiving placebo in regard to clinical factors such as duration of intensive care, total hospital stay and surgical frequency. However, 21 patients under 50 years of age showed a significantly lower blood transfusion requirement with the use of propantheline bromide.

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“…However, the operation mortality at emergency operation is high, especially in patients with haemorrhagic gastritis (5). This means that medical treatment almost always is primarily preferred.…”

Section: Introductionmentioning

confidence: 99%

Effect of Intravenous Infusion of Propantheline Bromide on Gastric Secretion

Furberg¹,

Krause²,

Rimsten³

1975

Upsala Journal of Medical Sciences

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The effect of 2 hours' intravenous infusion (7.5 mg/h) of propantheline bromide (Ercotina@, Erco Lakemedel AB) on basal or pentagastrin-stimulated gastric secretion was studied in 7 healthy subjects and in 11 patients with acute duodenal ulcer. A moderate to marked decrease in acid secretion rate and acid output was found both in subjects and patients during the infusion period. The acidity decreased in most of the subjects but did not change much in the patients. Two other dose rates (3.75 and 15 mglh) were studied in a few subjects and patients. The lowest dose rate gave as good an inhibition of the gastric secretion as the higher ones. No troublesome side effects were noticed. It was concluded that a dose rate of around 5-10 mg/h may be suitable for prolonged i.v. infusion, for example as trial therapy in patients with upper gastro-intestinal bleeding.

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Massive Bleeding Due to Acute Hemorrhagic Gastritis

Cited by 37 publications

References 7 publications

Suppressive Effect of Astaxanthin Isolated from theXanthophyllomyces dendrorhousMutant on Ethanol-Induced Gastric Mucosal Injury in Rats

Suppressive Effect of Astaxanthin Isolated from theXanthophyllomyces dendrorhousMutant on Ethanol-Induced Gastric Mucosal Injury in Rats

Propantheline Bromide in Massive Upper Gastrointestinal Haemorrhage

Effect of Intravenous Infusion of Propantheline Bromide on Gastric Secretion

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