Mass spectrometric investigation of the side-arm lariat effect of ortho- and para-methoxyphenoxymethyl-15-crown-5 in the gas phase

Recent advances in mass spectrometry studies of non-covalent complexes of macrocycles - A review

“…The Lariat ethers are crown ethers with an exocyclic electron-donating sidearm which provides additional coordination sites (figure 4d). A study of these derived 15-crown-5 with sodium salts was performed using MALDI-MS by Bradikhin et al [113] They investigated the interaction and the effect of the exocyclic methoxyphenoxymethyl substituent placed in ortho (ether 1), para (ether 2) and the unsubstituted crown (ether 3) in gas phase. Ethers 2 and 3 generated cluster ions of the composition [2M + 2Na + An] + (where M is the crown ether molecule and An is a monobasic anion) whereas ether 1 formed this type of clusters in residual amounts.…”