“…Recently, we have shown that OCT is the most sensitive marker in alcohol‐induced liver injury in rats, 18 which is generally accepted to have a common pathogenetic mechanism with NAFLD. In addition, marked elevation of OCT was observed in a mild model of NAFLD, including choline‐deficient diet feeding and a drug‐induced mitochondrial injury model; 19 therefore, the usefulness of OCT in another model where its pathogenesis is similar to human NAFLD is desired to confirm the universal superiority of OCT in the diagnosis of NAFLD having features of metabolic syndrome. In the present study, the clinical usefulness of OCT in NAFLD was further examined using diabetic obese mice.…”