Marine polymers-alginate/chitosan composited microcapsules for wound healing

Hydrogel-based treatments for spinal cord injuries

“…Yang et al crosslinked divalent Ca 2+ with sodium Alg and complexed it with CS using a polyelectrolyte to form microcapsules. The microcapsules exhibited good swelling, water absorption, degradation, and cargo release properties [ 38 ]. Hydrogen bond crosslinking is another common form of physical crosslinking.…”

Animal tissue-derived biomaterials for promoting wound healing

“…6b). 124 It is notable that CS-based wound dressings have important applications in wound hemostasis. As the electrostatic interaction wound exist between CS's amine groups and the red blood cell membranes' negative charges, which would lead to strong hemagglutination.…”

Physicochemical Features and Applicability of Newly Fabricated Phytopharmaceutical‐Loaded Hydrogel Alginate Microcarriers with Viscoelastic Polyelectrolyte Coatings

“…[13,14,21] Numerous studies have shown that polysaccharides, such as sodium alginate (ALG) and chitosan (CHIT), as well as synthetic PEs, such as poly(allylamine hydrochloride) (PAH), are promising materials for the fabrication of biocompatible microcarriers with improved biological properties. [13,[22][23][24] Such PEs possess high biodegradability and non-toxicity, as well as excellent filmforming capabilities and improve many biological processes, e. g., cell attachment. [25,26] Additionally, polysaccharides, e. g., CHIT, have several key functional roles, including unique hydration and mechanical properties, solubility in aqueous solutions, protein-repellent properties, and affinity to interact with bioactive molecules (growth factors).…”