Marine-inspired polymers in medical adhesion

Balkenende, Diederik W. R.; Winkler, Sally M.; Messersmith, Phillip B.

doi:10.1016/j.eurpolymj.2019.03.059

Cited by 106 publications

(64 citation statements)

References 128 publications

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“…Hence, inspiration to overcome these shortcomings came from the animal kingdom, and investigations on how marine animals adhere onto mineral or biological surfaces have been performed. The progress of this field of research has recently been reviewed by the Messersmith group [63]. Mussels are one example of marine animals that inspired humans to synthesise various materials as a medical adhesive exploiting the mechanism of how their byssi adhere to substrates.…”

Section: Pda As a Medical Adhesivementioning

confidence: 99%

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material

et al. 2020

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Biological structures have emerged through millennia of evolution, and nature has fine-tuned the material properties in order to optimise the structure-function relationship. Following this paradigm, polydopamine (PDA), which was found to be crucial for the adhesion of mussels to wet surfaces, was hence initially introduced as a coating substance to increase the chemical reactivity and surface adhesion properties. Structurally, polydopamine is very similar to melanin, which is a pigment of human skin responsible for the protection of underlying skin layers by efficiently absorbing light with potentially harmful wavelengths. Recent findings have shown the subsequent release of the energy (in the form of heat) upon light excitation, presenting it as an ideal candidate for photothermal applications. Thus, polydopamine can both be used to (i) coat nanoparticle surfaces and to (ii) form capsules and ultra-small (nano)particles/nanocomposites while retaining bulk characteristics (i.e., biocompatibility, stability under UV irradiation, heat conversion, and activity during photoacoustic imaging). Due to the aforementioned properties, polydopamine-based materials have since been tested in adhesive and in energy-related as well as in a range of medical applications such as for tumour ablation, imaging, and drug delivery. In this review, we focus upon how different forms of the material can be synthesised and the use of polydopamine in biological and biomedical applications. platform is highlighted ( Figure 1A). Then, theoretical and experimental proof of the chemical formation of polydopamine-based structures is summarised ( Figure 1B,C). This is then followed by descriptions of the unique (physicochemical) properties of polydopamine. Their applications as adhesive and in energy-related applications are also highlighted ( Figure 1D). Throughout, their wide range of applications in the biomedical field (thanks to their biocompatibility) is thoroughly explained. This includes examples of theranostic and drug delivery applications derived from different types of polydopamine-based configurations: adhesive, particle coating agent, capsule, and NPs/composites, respectively ( Figure 1C,E). Lastly, some challenges to make PDA into functional tools for future clinical applications are envisaged. Materials 2019, 12, x FOR PEER REVIEW 2 of 22polydopamine-based structures is summarised ( Figure 1B,C). This is then followed by descriptions of the unique (physicochemical) properties of polydopamine. Their applications as adhesive and in energy-related applications are also highlighted ( Figure 1D). Throughout, their wide range of applications in the biomedical field (thanks to their biocompatibility) is thoroughly explained. This includes examples of theranostic and drug delivery applications derived from different types of polydopamine-based configurations: adhesive, particle coating agent, capsule, and NPs/composites, respectively ( Figure 1C,E). Lastly, some challenges to make PDA into functional tools for future clinical applicatio...

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Section: Pda As a Medical Adhesivementioning

confidence: 99%

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material

et al. 2020

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“…They rely on highly viscous or solid adhesive secretions, usually containing specialized adhesive proteins [189]. By mimicking the use of said proteins, novel products can be developed for applications in dental, medical and industrial sectors for example [193][194][195].…”

Section: Adhesive Surfaces and Materials Inspired From Marine Organismsmentioning

confidence: 99%

“…Attachment is typically made via a byssus, a bundle of 50 to 100 adhesive threads and plaques secreted from a foot gland [196]. Once the target surface is selected, the mussel foot first adheres to the location, then secretes the byssus between the muscles within the shells and the attachment surface [194]. After complete adhesion, the foot generally retracts [197].…”

Section: Marine Mussel Adhesionmentioning

confidence: 99%

“…Several other medical adhesives inspired by marine coacervate formation have been developed and were recently reviewed elsewhere [194].…”

Section: Sandcastle Wormsmentioning

confidence: 99%

“…Many other marine organisms comprising octopus, barnacles, oysters and caddisfly larvae have developed adherence strategies and represent great sources of inspiration for the engineering of other adhesive materials [194,[221][222][223][224]. Biomimetic approaches can also combine the mechanisms of several species at a same time.…”

Section: Sandcastle Wormsmentioning

confidence: 99%

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Marine-Derived Polymeric Materials and Biomimetics: An Overview

et al. 2020

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The review covers recent literature on the ocean as both a source of biotechnological tools and as a source of bio-inspired materials. The emphasis is on marine biomacromolecules namely hyaluronic acid, chitin and chitosan, peptides, collagen, enzymes, polysaccharides from algae, and secondary metabolites like mycosporines. Their specific biological, physicochemical and structural properties together with relevant applications in biocomposite materials have been included. Additionally, it refers to the marine organisms as source of inspiration for the design and development of sustainable and functional (bio)materials. Marine biological functions that mimic reef fish mucus, marine adhesives and structural colouration are explained.

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Mimicking Nature

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2023

Biobased Adhesives

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Marine-inspired polymers in medical adhesion

Cited by 106 publications

References 128 publications

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material

Marine-Derived Polymeric Materials and Biomimetics: An Overview

Mimicking Nature

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