Marginal Donors in Renal Transplantation

Bozkurt, Birkan; Kılıç, Mehmet

doi:10.1016/j.transproceed.2015.04.006

Cited by 26 publications

(20 citation statements)

References 83 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our results corroborate the findings of several studies that have demonstrated the safety and ease of performing ex-vivo ureteroscopy prior to renal implantation. 10,13,14 With regards to small renal masses, one patient with an incidentally discovered 2 cm AML underwent ex-vivo partial nephrectomy and renorrhaphy. Ex-vivo partial nephrectomy for incidentally discovered renal masses with subsequent renal implantation has been described previously, with several reports demonstrating its applicability to small renal cell carcinomas.…”

Section: Discussionmentioning

confidence: 99%

Expanding living kidney donor criteria with ex-vivo surgery for renal anomalies

McGregor

Rampersad

Patel

2016

CUAJ

View full text Add to dashboard Cite

Introduction: Renal transplantation remains the gold standard treatment for end-stage renal disease, with living donor kidneys providing the best outcomes in terms of allograft survival. As the number of patients on the waitlist continues to grow, solutions to expand the donor pool are ongoing. A paradigm shift in the eligibility of donors with renal anomalies has been looked at as a potential source to expand the living donor pool. We sought to determine how many patients presented with anatomic renal anomalies at our transplant centre and describe the ex-vivo surgical techniques used to render these kidneys suitable for transplantation. Methods: A retrospective review was performed of all patients referred for surgical suitability to undergo laparoscopic donor nephrectomy between January 2011 and January 2015. Patient charts were analyzed for demographic information, perioperative variables, urological histories, and postoperative outcomes. Results: 96 referrals were identified, of which 81 patients underwent laparoscopic donor nephrectomy. Of these patients, 11 (13.6%) were identified as having a renal anomaly that could potentially exclude them from the donation process. These anomalies included five patients with unilateral nephrolithiasis, four patients with large renal cysts (>4 cm diameter), one patient with an angiomyolipoma (AML) and one patient with a calyceal diverticulum filled with stones. A description of the ex-vivo surgical techniques used to correct these renal anomalies is provided. Conclusions:We have shown here that ex-vivo surgical techniques can safely and effectively help correct some of these renal anomalies to render these kidneys transplantable, helping to expand the living donor pool.

show abstract

Section: Discussionmentioning

confidence: 99%

Expanding living kidney donor criteria with ex-vivo surgery for renal anomalies

McGregor

Rampersad

Patel

2016

CUAJ

View full text Add to dashboard Cite

show abstract

“…Die strenge Selektion der Lebendspender wird in neueren Studien in stark diskutiert [24][25][26][27][28]. Eine Lockerung der Kriterien könnte dem Problem des Organmangels entgegenwirken, ist jedoch auch mit höheren Risiken für Lebendspender und Empfänger verbunden [24]. Somit könnte sich die Wahrscheinlichkeit erhöhen, im Anschluss an eine Lebendspende unter körperlichen oder psychischen Einschränkungen zu leiden.…”

Section: Beziehung Zwischen Spender Und Empfängerunclassified

Wie bewerten Nierenlebendspender die Spende und deren Folgen? Eine Befragung von 144 Betroffenen

Schieber

Gaag

Heller

et al. 2018

Psychother Psych Med

View full text Add to dashboard Cite

Living organ donation becomes more and more important as the number of patients needing organ transplantation is increasing. The University Hospital of Erlangen initiated a survey of living kidney donors to improve the process of living donation. The survey aimed to assess the donor's needs and experiences during the process of living kidney donation. From 2003 to 2014 n=199 living kidney donations were registered at the University Hospital of Erlangen. A total of n=144 living kidney donors (65.3% females, mean age M=58.7 years) participated in the study. In general, the majority of the living kidney donors were satisfied with the process of donation. Almost all of them (98%) confirmed to donate again, if it was possible. A large part of the living kidney donors denied any negative physical or psychological consequences of the donation. However, around 25% reported still physical problems for example wound healing, pain or long-term hypertension. Furthermore, a lack of pre- and post-operative psychological care or a regular medical follow-up care was reported. Thus, clinical practice needs to be further developed to meet the patient's needs.

show abstract

“…Measures discussed include improving the allocation system, raising public awareness regarding organ donation, and the use of technologies to increase viability of organs with cold ischemia time. The use of non‐standard kidney donors, such as organs donated after cardiac death (DCD), ECDs, and after AKI, represents another possibility, and its applicability in practice is rising among adults . However, the question remains: are these strategies suitable for pediatric patients?…”

Section: Introductionmentioning

confidence: 99%

“…The use of non-standard kidney donors, such as organs donated after cardiac death (DCD), ECDs, and after AKI, represents another possibility, and its applicability in practice is rising among adults. 12 However, the question remains: are these strategies suitable for pediatric patients? The aim of the present review was to bring together the available data on the use of non-standard kidney donors for pediatric recipients.…”

Section: Introductionmentioning

confidence: 99%

Non‐standard criteria donors in pediatric kidney transplantation

Pereira

Nogueira

2019

Pediatric Transplantation

View full text Add to dashboard Cite

KT remains the treatment of choice for ESRD in children. However, the demand for kidney transplants continues to outstrip supply, even in the pediatric scenario. We reviewed the applicability of nonSCDs for pediatric KT. There is a lack of studies analyzing this modality among pediatric donors and recipients, where most conclusions are based on predictions from adult data. Nevertheless, marginal donors might be a reasonable option in selected cases. For example, the use of older LDs is an acceptable option, with outcomes comparable to SCDs. Organs donated after cardiac death represent another possibility, albeit with logistic, ethical, and legal limitations in some countries. AKI donors also constitute an option in special situations, although there are no pediatric data on these transplants. Likewise, there are no data on the use of expanded criteria donors in pediatric patients, but this appears not to be a good option, considering the compromised long‐term survival.

show abstract

Marginal Donors in Renal Transplantation

Cited by 26 publications

References 83 publications

Expanding living kidney donor criteria with ex-vivo surgery for renal anomalies

Expanding living kidney donor criteria with ex-vivo surgery for renal anomalies

Wie bewerten Nierenlebendspender die Spende und deren Folgen? Eine Befragung von 144 Betroffenen

Non‐standard criteria donors in pediatric kidney transplantation

Contact Info

Product

Resources

About