Mapping the Scientific Landscape of Diabetes Research in Malaysia (2000–2018): A Systematic Scientometrics Study

Objective The main purpose of this study was to investigate the pooled prevalence of prediabetes and type-2 diabetes in the general population of Malaysia. Method We systematically searched Medline (PubMed), Embase, Web of Science, Google Scholar and Malaysian Journals Online to identify relevant studies published between January 1, 1995, and November 30, 2021, on the prevalence of type-2 diabetes in Malaysia. Random-effects meta-analyses were used to obtain the pooled prevalence of diabetes and prediabetes. Subgroup analyses also used to analyze to the potential sources of heterogeneity. Meta- regression was carried to assess associations between study characteristics and diabetes prevalence. Three independent authors selected studies and conducted the quality assessment. The quality of the final evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Results Of 2689 potentially relevant studies, 786 titles and abstract were screened. Fifteen studies with 103063 individuals were eligible to be included in the meta-analyses. The pooled prevalence of diabetes was 14.39% (95% CI, 12.51%–16.38%; I2 = 98.4%, 103063 participants from 15 studies). The pooled prevalence of prediabetes was 11.62% (95% CI, 7.17%–16.97%; I2 = 99.8, 88702 participants from 9 studies). The subgroup analysis showed statistically significant differences in diabetes prevalence by the ethical sub-populations with highest in Indians (25.10%; 95% CI, 20.19%–30.35%), followed by Malays (15.25%; 95% CI, 11.59%–19.29%), Chinese (12.87%; 95% CI, 9.73%–16.37%), Bumiputeras (8.62%; 95% CI, 5.41%–12.47%) and others (6.91%; 95% CI, 5.71%–8.19%). There was no evidence of publication bias, although heterogeneity was high (I2 ranged from 0.00% to 99·8%). The quality of evidence based on GRADE was low. Conclusions Results of this study suggest that a high prevalence of prediabetes and diabetes in Malaysia. The diabetes prevalence is associated with time period and increasing age. The Malaysian government should develop a comprehensive approach and strategy to enhance diabetes awareness, control, prevention, and treatment. Trial registration Trial registration no. PROSPERO CRD42021255894; https://clinicaltrials.gov/.

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“…Table 1 summarizes the general characteristics of 15 selected studies [ 11 , 14 , 15 , 27 – 38 ]. In total, 103063 individuals were included.…”

Section: Resultsmentioning

confidence: 99%

“…Malaysia has the highest rate of diabetes in Western Pacific region and one of the highest in the world and costing around 600 million US dollars per year [ 10 , 11 ]. The prevalence of diabetes raised from 11.2% in 2011 to 18.3% in 2019, with a 68.3% increase [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of type-2 diabetes and prediabetes in Malaysia: A systematic review and meta-analysis

et al. 2022

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“…Recently, bibliometric analysis and data visualization have received a considerable amount of attention in biomedical fields owing to the explosion in basic and clinical data, and the growing number of freely available bibliometric tools over the past few years (24, 25). Taking DM and metabolic bone disorders as examples, multiple investigators have studied the scientific outputs and publication trends of diabetes-related research across different countries via bibliometric approaches (26)(27)(28). DM-associated complications such as diabetic foot ulcers (29), diabetic nephropathy (19,30), and diabetic ophthalmopathy (31), etc.…”

Section: Introductionmentioning

confidence: 99%

Mapping Knowledge Landscapes and Emerging Trends of the Links Between Bone Metabolism and Diabetes Mellitus: A Bibliometric Analysis From 2000 to 2021

Cheng

Guo

Yang

et al. 2022

Front. Public Health

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BackgroundDiabetes mellitus (DM) have become seriously threatens to human health and life quality worldwide. As a systemic metabolic disease, multiple studies have revealed that DM is related to metabolic bone diseases and always induces higher risk of fracture. In view of this, the links between bone metabolism (BM) and DM (BMDM) have gained much attention and numerous related papers have been published. Nevertheless, no prior studies have yet been performed to analyze the field of BMDM research through bibliometric approach. To fill this knowledge gap, we performed a comprehensive bibliometric analysis of the global scientific publications in this field.MethodsArticles and reviews regarding BMDM published between 2000 and 2021 were obtained from the Web of Science after manually screening. VOSviewer 1.6.16, CiteSpace V 5.8.R3, Bibliometrix, and two online analysis platforms were used to conduct the bibliometric and visualization analyses.ResultsA total of 2,525 documents including 2,255 articles and 270 reviews were retrieved. Our analysis demonstrated a steady increasing trend in the number of publications over the past 22 years (R2 = 0.989). The United States has occupied the leading position with the largest outputs and highest H-index. University of California San Francisco contributed the most publications, and Schwartz AV was the most influential author. Collaboration among institutions from different countries was relatively few. The journals that published the most BMDM-related papers were Bone and Osteoporosis International. Osteoporosis and related fractures are the main bone metabolic diseases of greatest concern in this field. According to co-cited references result, “high glucose environment,” “glycation end-product” and “sodium-glucose co-transporter” have been recognized as the current research focus in this domain. The keywords co-occurrence analysis indicated that “diabetic osteoporosis,” “osteoarthritis,” “fracture risk,” “meta-analysis,” “osteogenic differentiation,” “bone regeneration,” “osteogenesis,” and “trabecular bone score” might remain the research hotspots and frontiers in the near future.ConclusionAs a cross-discipline research field, the links between bone metabolism and diabetes mellitus are attracting increased attention. Osteoporosis and related fractures are the main bone metabolic diseases of greatest concern in this field. These insights may be helpful for clinicians to recognize diabetic osteopenia and provide more attention and support to such patients.

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“…In fact, Malaysia has the highest ratio of diabetes prevalence to total adult population in Western Pacific region. 19 Diabetes is one of the three major preventable health conditions included under the National Strategic Plan for the Non-Communicable Disease 2016-2025. 20 Furthermore, the total cost of diabetes management in Malaysia was estimated to be around USD 600 million per year.…”

Section: Discussionmentioning

confidence: 99%

Brain Wave Changes during Cognitive Task Performance in Uncomplicated Diabetic Adults: An Exploratory Study

Sim

Ahadon

Sohail

2022

imjm

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Introduction: Diabetes mellitus (DM) is a chronic disease associated with cognitive decline and dementia in the elderly population. This exploratory study analysed the brain wave changes during cognitive task performance in working adults with and without type 2 diabetes mellitus (T2DM). MATERIALS AND Methods: The Mini-Mental State Examination was used to screen subject’s cognitive function and quantitative electroencephalography was used to analyse subject’s brain waves at rest and whilst performing the serial seven test. Results: When performing the serial seven test, the diabetic group showed a higher absolute power of theta waves in the left frontal (Fp1, 16.22 ± 3.81 vs 3.75 ± 1.69; p = 0.022) and temporal regions (T3, 24.27 ± 3.69 vs 7.92 ± 2.17; p = 0.045), but lower absolute power of beta waves in both the frontal regions (Fp1, 27.35 ± 3.67 vs 41.14 ± 5.67; p = 0.029; Fp2, 23.01 ± 3.31 vs 39.05 ± 2.64; p = 0.041) and left temporal region (T3, 37.93 ± 4.64 vs 50.94 ± 3.56; p = 0.046) when compared to those of the control group. The diabetic group took longer to complete the task (127.9 ± 8.3 s vs 95.6 ± 5.9 s; p = 0.032) than the control group, despite no statistically significant difference in correct response rates. Diabetes duration was positively correlated with the theta/alpha ratio in the left frontal (Fp1, r = 0.525; p = 0.041) and temporal (T3, r = 0.618; p = 0.037) regions. Conclusions: T2DM may affect cognitive function in patients before clinical manifestation.

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Mapping the Scientific Landscape of Diabetes Research in Malaysia (2000–2018): A Systematic Scientometrics Study

Cited by 10 publications

References 28 publications

Prevalence of type-2 diabetes and prediabetes in Malaysia: A systematic review and meta-analysis

Prevalence of type-2 diabetes and prediabetes in Malaysia: A systematic review and meta-analysis

Mapping Knowledge Landscapes and Emerging Trends of the Links Between Bone Metabolism and Diabetes Mellitus: A Bibliometric Analysis From 2000 to 2021

Brain Wave Changes during Cognitive Task Performance in Uncomplicated Diabetic Adults: An Exploratory Study

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