Mapping mean and fluctuating velocities by Bayesian multipoint MR velocity encoding‐validation against 3D particle tracking velocimetry

Knobloch, V.; Binter, Christian; Gülan, Utku; Sigfridsson, Andreas; Holzner, Markus; Lüthi, Beat; Kozerke, Sebastian

doi:10.1002/mrm.24785

Cited by 33 publications

(38 citation statements)

References 34 publications

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“…In the preliminary study, the Siemens 4D PC-MRI sequence was found to eliminate TKE along the slice-direction because the sequence has nonsymmetric encoding around 2 axes. Therefore, we note that TKE in the present study could be lower in comparison with other studies that used other MR scanners5960.…”

Section: Methodscontrasting

confidence: 72%

The influence of the aortic valve angle on the hemodynamic features of the thoracic aorta

Kim

Kweon

et al. 2016

Sci Rep

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Since the first observation of a helical flow pattern in aortic blood flow, the existence of helical blood flow has been found to be associated with various pathological conditions such as bicuspid aortic valve, aortic stenosis, and aortic dilatation. However, an understanding of the development of helical blood flow and its clinical implications are still lacking. In our present study, we hypothesized that the direction and angle of aortic inflow can influence helical flow patterns and related hemodynamic features in the thoracic aorta. Therefore, we investigated the hemodynamic features in the thoracic aorta and various aortic inflow angles using patient-specific vascular phantoms that were generated using a 3D printer and time-resolved, 3D, phase-contrast magnetic resonance imaging (PC-MRI). The results show that the rotational direction and strength of helical blood flow in the thoracic aorta largely vary according to the inflow direction of the aorta, and a higher helical velocity results in higher wall shear stress distributions. In addition, right-handed rotational flow conditions with higher rotational velocities imply a larger total kinetic energy than left-handed rotational flow conditions with lower rotational velocities.

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Section: Methodscontrasting

confidence: 72%

The influence of the aortic valve angle on the hemodynamic features of the thoracic aorta

Kim

Kweon

et al. 2016

Sci Rep

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“…PIV measurements and the validation experiments were restricted to flow in a single plane. However, the present phantom setup is compatible with and can be extended to three‐dimensional laser techniques such as PTV, as recently used by Knobloch et al .…”

Section: Discussionmentioning

confidence: 99%

Independent validation of four‐dimensional flow MR velocities and vortex ring volume using particle imaging velocimetry and planar laser‐Induced fluorescence

Töger

Bidhult

Revstedt

et al. 2015

Magnetic Resonance in Med

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“…100 Since blood flow in the aorta is intricate, plenty of velocity measurements both in vitro and in vivo have been performed in the past years using different tools such as hot film, Doppler ultrasound, three-dimensional particle tracking velocimetry (3D-PTV) and phase contrast magnetic resonance imaging (PC-MRI). 26,35,48,49,66,81,82 The studies demonstrated that flow pattern in the ascending aorta was skewed and helical flow predominated in areas from the ascending aorta to the aortic arch in the systole. Kilner et al firstly used the three-directional phase contrast cine magnetic resonance velocity mapping to investigate the multidirectional flow velocities in the human aorta.…”

Section: Helical Flow In Human Vasculaturementioning

confidence: 97%

Physiological Significance of Helical Flow in the Arterial System and its Potential Clinical Applications

et al. 2014

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Helical flow in the human aorta is possibly a typical example of 'form follows function' in the vascular system. The helical blood flow may provide guaranties for the inner surface of the ascending aortic wall to get smooth and even washing by the blood so that atherosclerotic plaques can hardly form in the area of the ascending aorta. It has been documented that the phenomenon of helical flow of blood is not just localized in the ascending aorta, it also exists in several large arteries and veins as well. Preliminary studies demonstrated the widely existing helical flow might play positive physiological roles in facilitating blood flow transport, suppressing disturbed blood flow, preventing the accumulation of atherogenic low density lipoproteins on the luminal surfaces of arteries, enhancing oxygen transport from the blood to the arterial wall and reducing the adhesion of blood cells on the arterial surface. These roles of helical blood flow may lessen the burden of arteries and protect the arteries from the pathology of atherosclerosis, thrombosis, and intimal hyperplasia. The great development of time-resolved three-dimensional phase contrast MRI (flow-sensitive 4D-MRI) and the advent of dimensionless indices such as helical flow index proposed to characterize helical flow make clinic quantification of the helical flow in the human large arteries possible. Moreover, researchers probed into the possibility to apply the mechanism of helical flow to the design of vascular interventions to reduce thrombus formation and intimal hyperplasia caused by abnormal flow conditions.

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Mapping mean and fluctuating velocities by Bayesian multipoint MR velocity encoding‐validation against 3D particle tracking velocimetry

Cited by 33 publications

References 34 publications

The influence of the aortic valve angle on the hemodynamic features of the thoracic aorta

The influence of the aortic valve angle on the hemodynamic features of the thoracic aorta

Independent validation of four‐dimensional flow MR velocities and vortex ring volume using particle imaging velocimetry and planar laser‐Induced fluorescence

Physiological Significance of Helical Flow in the Arterial System and its Potential Clinical Applications

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