Mapping global acceptance and uptake of COVID-19 vaccination: A systematic review and meta-analysis

Abstract

Background The COVID-19 pandemic exit strategies depend on widespread acceptance of COVID-19 vaccines. We aim to estimate the global acceptance and uptake of COVID-19 vaccination, and their variations across populations, countries, time, and sociodemographic subgroups. Methods We searched four peer-reviewed databases (PubMed, EMBASE, Web of Science, and EBSCO) for papers published in English from December 1, 2019 to February 27, 2022. This review included original survey studies which investigated acceptance or uptake of COVID-19 vaccination, and study quality was assessed using the Appraisal tool for Cross-Sectional Studies. We reported the pooled acceptance or uptake rates and 95% confidence interval (CI) using meta-analysis with a random-effects model. Results Among 15690 identified studies, 519 articles with 7,990,117 participants are eligible for meta-analysis. The global acceptance and uptake rate of COVID-19 vaccination are 67.8% (95% CI: 67.1–68.6) and 42.3% (95% CI: 38.2–46.5), respectively. Among all population groups, pregnant/breastfeeding women have the lowest acceptance (54.0%, 46.3–61.7) and uptake rates (7.3%, 1.7–12.8). The acceptance rate varies across countries, ranging from 35.9% (34.3–37.5) to 86.9% (81.4–92.5) for adults, and the lowest acceptance is found in Russia, Ghana, Jordan, Lebanon, and Syria (below 50%). The acceptance rate declines globally in 2020, then recovers from December 2020 to June 2021, and further drops in late 2021. Females, those aged < 60 years old, Black individuals, those with lower education or income have the lower acceptance than their counterparts. There are large gaps (around 20%) between acceptance and uptake rates for populations with low education or income. Conclusion COVID-19 vaccine acceptance needs to be improved globally. Continuous vaccine acceptance monitoring is necessary to inform public health decision making.

COVID-19 Vaccine Booster Dose Acceptance: Systematic Review and Meta-Analysis

“…The overall acceptance rate of booster COVID-19 vaccination among 198,831 subjects across 48 studies conducted in 23 countries was 81% (95% CI: 75–85%). This rate was higher compared with the recent and earlier estimates of COVID-19 vaccine acceptance, which ranged from 60% to 75% in various meta-analyses [ 85 , 93 , 94 ]. This higher estimated proportion of accepting the booster dose of COVID-19 vaccination can be related to the timing of the included studies, which were conducted in a recent time period compared with earlier studies tackling COVID-19 vaccine acceptance.…”

Health Belief Model and parents' acceptance of the Pfizer-BioNTech and Sinopharm COVID-19 vaccine for children aged 5–18 years Old: A national survey

“…Vaccine acceptance for Pfizer-BioNTech in our study was higher than in Brazil (61.4%) [15] and Turkey (36.3%) [7] , while the highest vaccine acceptance rate was in the United States (99.3%) and Mexico (95.2%). Studies in Asian countries show that 58.3% of parents accepted the COVID-19 vaccine for their children.…”

“…The estimated worldwide vaccine acceptance rate for children and adolescents was 70.7%. [7] Vaccine hesitancy in low- and middle-income countries (LMIC) was high, leading to hospitalizations and mortality. [8] Parents' attitude toward vaccine hesitancy was associated with a lack of trust in COVID-19 vaccine safety and efficacy.…”

¿Es Perú el país con mayor tasa de mortalidad en el mundo?: un análisis situacional

“…Existen grandes brechas (alrededor del 20%) entre las tasas de aceptación y la aplicación de las vacunas para las poblaciones con baja educación o ingresos. 6 En el Perú la vacuna se aplica desde el 9 de febrero de 2021. Ese día se aplicó la vacuna contra COVID-19 del laboratorio chino Sinopharm a 3 842 personas, empezando con el personal de salud que se hallaba en la primera línea de atención.…”