Mapping Corneal Thickness Using Dual-Scheimpflug Imaging at Different Stages of Keratoconus

Demir, Selim; Ortak, Hüseyin; Yeter, Volkan; Alim, Sait; Sayn, Osman; Taş, Ufuk; Sonmez, B.

doi:10.1097/ico.0b013e3182a7387f

Cited by 20 publications

(10 citation statements)

References 28 publications

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“…Wolffsohn et al and Demir et al also found a negative correlation between stage of keratoconus and corneal thickness [22, 23]. In our study all of the subgroups showed significantly high correlations between measurements of the 2 devices ( P < 0.001) and the greatest difference was at the CT 8 mm in all stages of keratoconus.…”

Section: Discussionsupporting

confidence: 70%

Evaluation of Pachymetric Measurements with Scheimpflug Photography-Based System and Optical Coherence Tomography Pachymetry at Different Stages of Keratoconus

Akçay

Ozgurhan

Bozkurt

et al. 2014

Journal of Ophthalmology

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Section: Discussionsupporting

confidence: 70%

Evaluation of Pachymetric Measurements with Scheimpflug Photography-Based System and Optical Coherence Tomography Pachymetry at Different Stages of Keratoconus

Akçay

Ozgurhan

Bozkurt

et al. 2014

Journal of Ophthalmology

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“…Detection of corneal ectatic disorders as early on as possible is necessary to prevent, or delay, the progression of keratoconus. Some studies claim to distinguish SCKC from normal eyes using topographic parameters [ 34 , 35 , 36 ] and others state that there is an overlap between topographic data obtained from a SCKC group and a normal group [ 37 , 38 ]. As a result, biomechanical data could improve the detection and severity prediction of keratoconus.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Intraocular Pressure and Other Biomechanical Parameters to Distinguish between Subclinical Keratoconus and Healthy Corneas

Peris-Martínez

Dı́ez-Ajenjo

García-Domene

et al. 2021

JCM

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(1) Purpose: To assess the main corneal response differences between normal and subclinical keratoconus (SCKC) with a Corvis® ST device. (2) Material and Methods: We selected 183 eyes of normal patients, of a mean age of 33 ± 9 years and 16 eyes of patients with SCKC of a similar mean age. We measured best corrected visual acuity (BCVA) and corneal topography with a Pentacam HD device to select the SCKC group. Biomechanical measurements were performed using the Corvis® ST device. We carried out a non-parametric analysis of the data with SPSS software (Wilcoxon signed rank-test). (3) Results: We found statistically significant differences between the control and SCKC groups in some corneal biomechanical parameters: first and second applanation time (p = 0.05 and p = 0.02), maximum deformation amplitude (p = 0.016), highest concavity radius (p = 0.007), and second applanation length and corneal velocity ((p = 0.039 and p = 0.016). (4) Conclusions: Our results show that the use of normalised biomechanical parameters provided by noncontact tonometry, combined with a discriminant function theory, is a useful tool for detecting subclinical keratoconus.

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“…The Pentacam Scheimpflug camera asseses the curvature and elevation of the anterior and posterior corneal surface as well as pachymetry with high reproducibility and repeatability [11] , [12] . Several studies have proved high accuracy of posterior elevation measurements in detecting keratoconus [13] – [17] and some reported pachymetry as a sensitive parameter to detect progressive changes in keratoconus [18] – [24] . In addition, relational thickness profile was found to be superior to single-point pachymetric data in discriminating normal corneas from those with keratoconus [25] , [26] .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Intereye Corneal Asymmetry in Patients with Keratoconus. A Scheimpflug Imaging Study

et al. 2014

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PurposeTo assess the correlation between keratoconus severity and intereye asymmetry of pachymetric data and posterior elevation values and to evaluate their combined accuracy in discriminating normal corneas from those with keratoconus.MethodsThis study included 97 patients: 65 subjects with bilateral normal corneas (NC) and 32 with keratoconus (KC). Central corneal thickness (CCT), thinnest corneal thickness (ThCT) and posterior elevation (PE) at the thinnest point of the cornea were measured in both eyes using Scheimpflug imaging. Intereye asymmetry and its correlation with keratoconus severity were calculated for each variable. The area under the receiver operating characteristic curve (AUROC) was used to compare predictive accuracy of different variables for keratoconus.ResultsIn normal eyes, intereye differences were significantly lower compared with the keratoconus eyes (p<0.001, for CCT, ThCT and PE). There was a significant exponential correlation between disease severity and intereye asymmetry of steep keratometry (r2 = 0.55, p<0.001), CCT (r2 = 0.39, p<0.001), ThCT (r2 = 0.48, p<0.001) and PE (r2 = 0.64, p<0.001). After adjustment for keratoconus severity, asymmetry in thinnest pachymetry proved to be the best parameter to characterize intereye corneal asymmetry in keratoconus. This variable had high accuracy and significantly better discriminating ability (AUROC: 0.99) for KC than posterior elevation (AUROC: 0.96), ThCT (AUROC: 0.94) or CCT (AUROC: 0.92) alone.ConclusionsThere is an increased intereye asymmetry in keratometry, pachymetry and posterior corneal elevation values in keratoconic patients compared to subjects with normal corneas. Keratoconus patients with more severe disease are also more asymmetric in their disease status which should be taken into account during clinical care.

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Mapping Corneal Thickness Using Dual-Scheimpflug Imaging at Different Stages of Keratoconus

Abstract: The data obtained by dual-Scheimpflug imaging for the corneal thicknesses of the entire cornea provide useful information for grading the severity of keratoconus.

Cited by 20 publications

References 28 publications

Evaluation of Pachymetric Measurements with Scheimpflug Photography-Based System and Optical Coherence Tomography Pachymetry at Different Stages of Keratoconus

Evaluation of Pachymetric Measurements with Scheimpflug Photography-Based System and Optical Coherence Tomography Pachymetry at Different Stages of Keratoconus

Evaluation of Intraocular Pressure and Other Biomechanical Parameters to Distinguish between Subclinical Keratoconus and Healthy Corneas

Evaluation of Intereye Corneal Asymmetry in Patients with Keratoconus. A Scheimpflug Imaging Study

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