Manufacturer identification and storage time determination of “Dong’e Ejiao” using near infrared spectroscopy and chemometrics

Zuo

Journal of Chemometrics

2020

Herbal medicine has obtained great attention for its effective efficacy using its crude materials and patent medicines. It is believed that the efficacy is a synergetic action by several chemical components. To present a detailed overview of the usage of multivariate statistical techniques developed for analytical chemistry in quality assessment and origins traceability, we provided an extensive pragmatic and practical overview of these techniques for the quality control of these crude medicines. Two pattern recognition methods, unsupervised and supervised approaches, were interpreted using practical instances. Overall, the review briefly summarized common applications for location, species, harvesting time, processed production, manufacture, botanical part, and authenticity. Besides, we focused on data pretreatment and fusion strategies listing recently published literature to provide a detailed reference to choose the most appropriate statistical method and fusion strategies. Actual applications have proved chemometrics as an effective and rapid tool for the quality control of herbal medicine.

Section: Applications Of Chemometrics In Tcmmentioning

confidence: 99%

Pattern recognition: An effective tool for quality assessment of herbal medicine based on chemical information

Zuo

Journal of Chemometrics

2020

“…Deferrichrysin can be used in food as a food supplement, to prevent colour change and to create iron-fortified foods [ 89 ]. A component of traditional Chinese medicine, A ’Jiao ( Collacoriiasini , donkey-hide gelatine), has been used to enrich the blood for thousands of years in China [ 90 ]. Egg white protein is useful for recovery of IDA in SD rats [ 98 ].…”

Section: Usages Advantages and Challenges Of Protein Hydrolysatesmentioning

confidence: 99%

Protein Hydrolysates as Promoters of Non-Haem Iron Absorption

Jiang

Huang

2017

Nutrients

Iron (Fe) is an essential micronutrient for human growth and health. Organic iron is an excellent iron supplement due to its bioavailability. Both amino acids and peptides improve iron bioavailability and absorption and are therefore valuable components of iron supplements. This review focuses on protein hydrolysates as potential promoters of iron absorption. The ability of protein hydrolysates to chelate iron is thought to be a key attribute for the promotion of iron absorption. Iron-chelatable protein hydrolysates are categorized by their absorption forms: amino acids, di- and tri-peptides and polypeptides. Their structural characteristics, including their size and amino acid sequence, as well as the presence of special amino acids, influence their iron chelation abilities and bioavailabilities. Protein hydrolysates promote iron absorption by keeping iron soluble, reducing ferric iron to ferrous iron, and promoting transport across cell membranes into the gut. We also discuss the use and relative merits of protein hydrolysates as iron supplements.

J. Zhejiang Univ. Sci. B

“…It has already shown a great application in the analysis of chemical (Islam et al, 2015) and biological medicines (Wang F. et al, 2015). When it comes to traditional Chinese medicines (TCMs), NIRS was successfully used for quantitative assays and identification (Li et al, 2016) and classification of TCMs (Wang and Yu, 2015). Moreover, NIRS is frequently adopted on-or at-line in different manufacturing units such as decoction (Wu et al, 2011), alcohol precipitation (Huang and Qu, 2011), and quality inspection of final products .…”

Section: Introductionmentioning

confidence: 99%

Rapid quantification of multi-components in alcohol precipitation liquid of Codonopsis Radix using near infrared spectroscopy (NIRS)

Luo

Huang³

et al. 2017

Self Cite

A near infrared spectroscopy (NIRS) approach was established for quality control of the alcohol precipitation liquid in the manufacture of Codonopsis Radix. By applying NIRS with multivariate analysis, it was possible to build variation into the calibration sample set, and the Plackett-Burman design, Box-Behnken design, and a concentrating-diluting method were used to obtain the sample set covered with sufficient fluctuation of process parameters and extended concentration information. NIR data were calibrated to predict the four quality indicators using partial least squares regression (PLSR). In the four calibration models, the root mean squares errors of prediction (RMSEPs) were 1.22 μg/ml, 10.5 μg/ml, 1.43 μg/ml, and 0.433% for lobetyolin, total flavonoids, pigments, and total solid contents, respectively. The results indicated that multi-components quantification of the alcohol precipitation liquid of Codonopsis Radix could be achieved with an NIRS-based method, which offers a useful tool for real-time release testing (RTRT) of intermediates in the manufacture of Codonopsis Radix.