Manometric Studies of the Human Pylorus

Relationships of human antroduodenal motility and transpyloric fluid movement: non-invasive observations with real-time ultrasound.

“…Manometric methods permit observation of the timing and magnitude of pressure changes within the gastric lumen'l and some electrical recordings from the human stomach and duodenum have been obtained2 5 6 but although both of these give information about muscle contraction, they do not identify the movement of intragastric contents. Simultaneous studies of antral contractions and gastric emptying in man have been undertaken using intubation methods,5 7 and also with a scintigraphic procedure,8 9 but much of the current knowledge about the relationships between flow of luminal contents and contractions of the human stomach, pylorus, and duodenum has been obtained from radiological investigations using contrast media.…”

Fecal control following pyloric valve transposition after abdominoperineal resection

“…There is even the possibility that the PV, when used to replace an excised rectal sphincter, may not act as a true sphincter but simply functions as a relative obstruction that impedes fecal passage until there is a propulsive force exerted by proximal colonic peristalsis [5,6].…”

The Manometric Findings at the Human Pylorus: The evidence against the Presence of a Tonic Sphincter

“…A tube assembly similar to that used by Fisher & Cohen (l), and Kaye et al (2), with some modifications, was constructed. Four polyethylene catheters were bonded, and the sealed ends inserted into the mercury head of an AN-20 Anderson duodenal tube.…”

“…Four side holes or orifices (diameter, 1.5 mm), one in each catheter, were placed at 6,9,12, and 15 cm from the tip of the tube assembly and oriented radially. Each catheter was perfused with saline by a syringe pump at 1.1 ml/min, as used by Fisher & Cohen (1) and Kaye et al (2), and connected through three-way taps to pressure transducers (Elkomatic) and through a calomel half-cell to a Vibron voltmeter. The output of both was recorded on a Devices multichannel recorder (see Fig.…”

“…In five, pyloric pressure was measured by balloons; only one found any evidence of an HPZ (in 5% of tests) (1@-14). In six subsequent studies perfused catheters were used, and five found evidence of an HPZ (1,2,(15)(16)(17)(18). Balloons, although less accurate in measuring sphincter pressure, are not less sensitive than perfused catheters in sphincter recognition (6).…”