Manipulation of microparticles for construction of array patterns by negative dielectrophoresis using multilayered array and grid electrodes

Ino, Kosuke; Shiku, Hitoshi; Ozawa, Fumisato; Yasukawa, Tomoyuki; Matsue, Tomokazu

doi:10.1002/bit.22445

Cited by 24 publications

(16 citation statements)

References 28 publications

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“…Several methods for particle patterning use electrophoretic and dielectrophoretic forces . The particle patterning from a suspension onto a surface by negative dielectrophoresis and positive dielectrophoresis using a template electrode only allows for the generation of fixed particle patterns . In another approach, it is shown that, using a low voltage complementary metal oxide semiconductor (CMOS) chip technique, it is possible to manipulate and investigate single particles or cells via dielectrophoretic forces .…”

Section: Electrical Particle Patterningmentioning

confidence: 99%

Combinatorial Particle Patterning

Bojničić-Kninski

Popov

Dörsam

et al. 2017

Adv Funct Materials

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The unique properties of solid particles make them a promising element of micro-and nanostructure technologies. Solid particles can be used as building blocks for micro and nanostructures, carriers of monomers, or catalysts. The possibility of patterning different kinds of particles on the same substrate opens the pathway for novel combinatorial designs and novel technologies. One of the examples of such technologies is the synthesis of peptide arrays with amino acid particles. This review examines the known methods of combinatorial particle patterning via static electrical and magnetic fields, laser radiation, patterning by synthesis, and particle patterning via chemically modified or microstructured surfaces.

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Section: Electrical Particle Patterningmentioning

confidence: 99%

Combinatorial Particle Patterning

Bojničić-Kninski

Popov

Dörsam

et al. 2017

Adv Funct Materials

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“…[87][88][89] We reported the development of a novel DEP-based chip device containing IDA electrodes (DEPIDA) for producing a cell culture array with paired cells. 87 The chip-based device consists of an array of 900 gourd-shaped microwells and IDA electrodes.…”

Section: Dep-based Devices For Bioanalysismentioning

confidence: 99%

Microchemistry- and MEMS-based Integrated Electrochemical Devices for Bioassay Applications

Ino

2015

Electrochemistry

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Here, we present an overview of our recent research progress in development of electrochemical devices/systems for bioassays. These devices/systems are based on microchemistry and micro-electromechanical systems (MEMS) for sophisticated analytical and electrochemical measurements. In particular, we exploit the unique chemical reactions occurring in micrometer-size spaces and/or involving micrometer-size structures for bioassays, including cell analyses. This paper addresses five topics: probe-, chip-, large-scale-integration chip-, and dielectrophoresisbased devices, and electrodeposition of hydrogels for bioassays.

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“…DEP has been used as a force for a variety of advanced manipulation systems for micro-and nano-objects, including the patterning of the microparticles and cells by using p-DEP [3]- [8] and n-DEP [9]- [14], single-particle manipulation [15]- [18] and sorting, capture, navigation and separation of particles in microfluidic systems [19]- [32]. Field-flow fractionation (FFF) has been used for separating macromolecules, particles and living cells [19]- [21].…”

Section: Introductionmentioning

confidence: 99%

Negative Dielectrophoretic Particle Positioning in A Fluidic Flow

Yasukawa¹,

Yamada²,

Shiku³

et al. 2012

Intelligent Automation & Soft Computing

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In this work, we report the control of a microparticle position within fluid flow based on its size by using a repulsive force generated with negative dielectrophoresis (n-DEP). The n-DEP based fluidic channel, which was consisted of navigator and separator electrodes, was used to manipulate the particle flow in the center of channel and to control the particle position in the fluidic flow. The mixture of 10 µm-and 20 µm-diameter particles was introduced into the channel with 30 µm height at 700 µm/s. On applying an AC voltage (23 V peak-peak and 7 MHz) to the navigator electrodes on the upper and lower substrates in a n-DEP frequency region, the suspended microparticles were guided to the center of the fluidic channel and then channelled through the passage gate positioned at the center of the channel. The AC electric field was also applied to separator electrodes, resulting in a formation of flow paths with low electric fields. The separator was consisted of the five band electrodes with the different gap spaces with the adjacent band, which allow to forming the flow paths with different electric fields. The microparticles separately flow in line along the paths formed between the band electrodes, the 10 µm-diameter particles mainly flow through the narrow path and 20 µm-diameter particles through the wide path arranged at the outside from the center. These results indicated that positions of two types of microparticles in the fluidic channel were easily separated and controlled using the n-DEP. The present procedure therefore yields a procedure for the DEP based simple and miniaturized separators.

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Manipulation of microparticles for construction of array patterns by negative dielectrophoresis using multilayered array and grid electrodes

Cited by 24 publications

References 28 publications

Combinatorial Particle Patterning

Combinatorial Particle Patterning

Microchemistry- and MEMS-based Integrated Electrochemical Devices for Bioassay Applications

Negative Dielectrophoretic Particle Positioning in A Fluidic Flow

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