Mango Dermatitis After Urushiol Sensitization

Yoo, Michael J.; Carius, Brandon M

doi:10.5811/cpcem.2019.6.43196

Cited by 8 publications

(9 citation statements)

References 8 publications

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“…Hershko et al [ 97 ] reported the fact the individual with prior exposure to poison ivy/oak allergy may develop allergic contact dermatitis from mango on first exposure. Cross-sensitization of these plants with mango is known to be secondary to a superposition of urushiol antigen and 5-resorcinol, primarily found in mango peels [ 98 ]. These studies overall suggest that mango has some allergic responses, but those reactions have been limited to mango latex, pollen allergen, or prior urushiol exposure [ 99 ].…”

Section: Toxicological/allergenicity Evaluation Of Mlsmentioning

confidence: 99%

Mango (Mangifera indica L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities

et al. 2021

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Mangifera indica L. belongs to the family of Anacardiaceae and is an important fruit from South and Southeast Asia. India, China, Thailand, Indonesia, Pakistan, Mexico, Brazil, Bangladesh, Nigeria, and the Philippines are among the top mango producer countries. Leaves of the mango plant have been studied for their health benefits, which are attributed to a plethora of phytochemicals such as mangiferin, followed by phenolic acids, benzophenones, and other antioxidants such as flavonoids, ascorbic acid, carotenoids, and tocopherols. The extracts from mango leaves (MLs) have been studied for their biological activities, including anti-cancer, anti-diabetic, anti-oxidant, anti-microbial, anti-obesity, lipid-lowering, hepato-protection, and anti-diarrheal. In the present review, we have elaborated on the nutritional and phytochemical profile of the MLs. Further, various bioactivities of the ML extracts are also critically discussed. Considering the phytochemical profile and beneficial effects of the MLs, they can be used as a potential ingredient for the development of functional foods and pharmaceutical drugs. However, more detailed clinical trials still needed to be conducted for establishing the actual efficacy of the ML extracts.

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Section: Toxicological/allergenicity Evaluation Of Mlsmentioning

confidence: 99%

Mango (Mangifera indica L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities

et al. 2021

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“…Contact dermatitis can occur on the first exposure to mango due to previous sensitisation to urushiol-containing plants, primarily those in the Anacardiaceae family. Seven patients had previous known sensitisation to poison ivy, poison oak and Lithracea caustica [16,17,31,36,38,40,41]. There was one case where the patient had no known sensitisation to urushiol containing plants, but nevertheless tested positive for urushiol 0.01% in petrolatum at patch testing [28].…”

Section: Discussionmentioning

confidence: 99%

“…Of the 30 patients described above, 23 had been in direct contact with the mango fruit, skin, stem, sap, or even the tree itself [16][17][18]28,36]. The remaining patients had ingested mango either peeled or unpeeled, fresh or processed in the form of mango gelato [1,28,29,31,34,35,[37][38][39][40][41][42]. Patients who had been in direct contact with mango developed skin lesions at contact site, presenting as pruritic and erythematous rash, with occasional vesicles and bullae on the extremities or on the lips, and in the perioral area.…”

Section: Discussionmentioning

confidence: 99%

“…In case of mango ingestion, patients developed lesions consistent either with localised contact dermatitis (perioral skin lesions associated with occasional lip and facial edema), or with disseminated dermatitis (patients displaying skin lesions in areas that were not in contact with the fruit) [35,38,42]. It was previously thought that perioral lesions can develop if the fruit is eaten whole, without removal of the skin, thus the fruit could be enjoyed if peeled by another person [43].…”

Section: Discussionmentioning

confidence: 99%

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Contact Allergy Induced by Mango (Mangifera indica): A Relevant Topic?

et al. 2021

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Introduction: The most common clinical manifestation of mango allergy is contact dermatitis, which can be localized or systemic. The sensitising substances that have long been suspected are alk(en)yl catechols and/or alk(en)yl resorcinols. Methods: We reviewed the original articles published on Pubmed, Embase and Cochrane Library before 15 September 2021, on the topic of contact allergy induced by mango and we synthesized the key data. Results: We found 12 case reports and four case series, with a total of 37 patients. Only seven of these cases were reported in patients from mango-cultivating countries, the other 30 were from countries where mango cultivation does not occur, and 26 were also from countries where poison ivy/oak are commonly found. We found that contact dermatitis may occur on the first exposure to mango due to previous sensitisation to urushiol-containing plants. The diagnosis was confirmed by patch testing in some of the cases. There was great heterogeneity between the reagents used. Conclusion: Mango fruit is frequently consumed, but mango induced contact dermatitis, the main hypersensitivity reaction induced by mango, is rare. Further data is necessary for a better understanding of sensitising substances and, consecutively, standardization of patch test reagents.

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“…Exposure to the urushiol in Toxicodendron radicans can cause hypersensitivity in related plants, such as mango, Mangifera indica ( Yoo & Carius, 2019 ), and the Chinese Lacquer Tree, Toxicodendron vernicifluum . Consumer products made from the Chinese Lacquer Tree are manufactured by curing the urushiol-containing sap to a clear, hard, waterproof substance.…”

Section: Introductionmentioning

confidence: 99%

The complete genome sequence of Toxicodendron radicans, Eastern Poison Ivy

Pirro

2020

F1000Res

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Eastern Poison Ivy (Toxicodendron radicans, Anacardiaceae) is well known in Eastern North America for causing contact dermatitis, an itchy and painful rash in most people who come in contact with it. We present the whole genome sequence and annotation of this species. A total of 96,255,779 paired-ends reads consisting of 28.9 G bases were obtained by sequencing one leaf from a wild-collected plant. The reads were assembled by a de novo method followed by alignment to related species. Annotation was performed via GenMark-ES. The raw and assembled data is publicly available via GenBank: Sequence Read Archive (SRR10325927) and Assembly (GCA_009867345).

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Mango Dermatitis After Urushiol Sensitization

Cited by 8 publications

References 8 publications

Mango (Mangifera indica L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities

Mango (Mangifera indica L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities

Contact Allergy Induced by Mango (Mangifera indica): A Relevant Topic?

The complete genome sequence of Toxicodendron radicans, Eastern Poison Ivy

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