2022
DOI: 10.1039/d1tb02646a
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Manganese oxide nanomaterials for bacterial infection detection and therapy

Abstract: This review presents applications of MnO2 nanomaterials in anti-infective detection and therapy. Firstly, the antibacterial mechanism are summarized. Moreover, the applications are highlighted. Finally, the challenges and perspectives are discussed.

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Cited by 29 publications
(15 citation statements)
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“…4 Nevertheless, the overuse of antibiotics resulted in the occurrence of drug-resistant bacterial pathogens, which greatly reduced the therapeutic effects of traditional antibiotics. 5,6 Hence, there is an imperative need to exploit alternative antimicrobial agents and strategies that can realize both killing bacteria and preventing drug resistance for bacterial infectionrelated disease treatment.…”
Section: Introductionmentioning
confidence: 99%
“…4 Nevertheless, the overuse of antibiotics resulted in the occurrence of drug-resistant bacterial pathogens, which greatly reduced the therapeutic effects of traditional antibiotics. 5,6 Hence, there is an imperative need to exploit alternative antimicrobial agents and strategies that can realize both killing bacteria and preventing drug resistance for bacterial infectionrelated disease treatment.…”
Section: Introductionmentioning
confidence: 99%
“…Consequently, how to deal with these critical issues will be crucial for the study of MTKIs. As we all know, nanotechnology has gained widespread attention owing to its efficient, minimally invasive, and multifunctional properties, and it could fulfill higher specific drug delivery with minimum undesirable effects [ 3 , [18] , [19] , [20] , [21] , [22] ]. It seems quite attractive to cope with these oncologic therapy problems of MTKIs through nanomedicine technology.…”
Section: Introductionmentioning
confidence: 99%
“…In the fields of biomedicine, biological contamination can be easily found on devices such as sensors, , interventional catheters, or bone materials, , leading to inflammatory reactions, , rejection reactions, and bacterial infections . Among them, bacterial infections are a critical factor leading to the failure of clinical application of biological materials, , which are called healthcare-related infections (HAIs). Taking implantation or long-term interventional catheters as an example, pathogens are extremely easy to invade and spread, causing infections.…”
Section: Introductionmentioning
confidence: 99%