Manfaat Sirih Merah (Piper crocatum)sebagai Agen Anti Bakterial terhadap Bakteri Gram Positif dan Bakteri Gram Negatif

Rachmawaty, Farida Juliantina; Citra, Dewa Ayu; Nirwani, Bunga; Nurmasitoh, Titis; Bowo, Endrawati Tri

doi:10.20885/jkki.vol1.iss1.art3

Cited by 14 publications

(5 citation statements)

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“…Flavonoid mengganggu fungsi membrane sel dengan cara denaturasi, yaitu perubahan bentuk normal protein akibat terputusnya ikatan hydrogen [10]. Alkaloid menghambat pertumbuhan bakteri dengan cara mengganggu komponen pada penyusun peptidoglikan sel bakteri [11]. Lalu untuk tanin sendiri menghambat pertumbuhan bakteri melalui interaksi ikatan hidrofobik dimana ikatan hidrofobik ini akan menyebabkan denaturasi dan membuat metabolisme sel terganggu [10].…”

Section: Pendahuluanunclassified

Uji Aktivitas Antibakteri Ekstrak Etanol Daun Ungu (Graptophyllum pictum (L) Griff) terhadap Pertumbuhan Streptococcus sanguinis

Syahrani,

Kurniawati,

Prihanti

et al. 2024

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Streptococcus sanguinis has strong adhesion with salivary pellicles which causes other oral bacteria to attach more and has contribution in causing caries and periodontal disease. S. sanguinis mediated the adhesion of S. mutans to dental pellicle receptors so inhibiting the interaction between S. sanguinis and S. mutans would prevent the risk of dental caries. Purple leaf (Graptophyllum pictum) is one of the medicinal plants or natural ingredients that are useful as antibacterials. The purpose of this study was to examine antibacterial activity of purple leaf extract against S. sanguinis. This experimental laboratory study with a pre-posttest control group design was conducted by dilution method on treatment groups, purple leaf extract with concentrations of 25%, 12.5%, 6.25% and 3.12%. Visual and spectrophotometer examination was observed before and after incubation.The result showed that purple leaf extract with concentrations of 6.25% and 3.12% and control + groups had not turbidity and decreased absorbance value. Furthermore, the One Way Anova parametric statistical test and also Post-Hoc Least Significant Difference showed that there were significant differences between the study groups. The purple leaf extract (Graptophyllum pictum L. Griff) had antibacterial activity against S. sanguinis. The antibacterial test for extracts that are dark in color can be continued using the TVC (Total Viable Count) method to provide a quantitative estimate of the concentration of bacterial cells in the sample in units of CFU/ml.

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Section: Pendahuluanunclassified

Uji Aktivitas Antibakteri Ekstrak Etanol Daun Ungu (Graptophyllum pictum (L) Griff) terhadap Pertumbuhan Streptococcus sanguinis

Syahrani,

Kurniawati,

Prihanti

et al. 2024

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“…Flavonoid sebagai antibakteri memiliki kemampuan mendenaturasi protein sel bakteri dan merusak membran sel yang menyebabkan sel menjadi lisis [13]atau pecah dengan cara membentuk senyawa kompleks terhadap protein extraseluler yang mengganggu keutuhan membran sel bakteri yaitu dengan cara mendenaturasi protein sel bakteri dan merusak membran sel tanpa dapat diperbaiki kembali [14].…”

Section: Hasil Dan Pembahasanunclassified

Review Artikel : Aktivitas Antibakteri Daun Mangkokan (Nothopanax scutellarium)

Oktaviani,

Al Zahra

2024

JSSCR

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Mangkokan leaves (Nothopanax scutellarium) are one of the ornamental plants in the yard. One of its benefits is that it is antibacterial. The use of antibacterials has been widely used to inhibit the growth of bacteria, but antibiotic resistance against bacteria continues to increase. The purpose of this review article is to examine the extent to which mangkokan leaves (Nothopanax scutellarium) have been tested as antibacterial and to examine secondary metabolites that have an antibacterial role. This research took the form of an article search carried out based on inclusion and exclusion criteria. The inclusion criteria used were articles published within a 10 years span. Based on article search results, mangkokan leaves (Nothopanax scutellarium) have been proven to be able to inhibit the growth of several bacteria including Staphylococcus aureus, Eschericia coli, Staphylococcus epidermidis, Pseudomonas aeruginosa, Propionobacterium acne, Salmonella gastroenterit, Lactobacilus rhamnosus and Bacillus subtilis. Secondary metabolites that have an active role as antibacterials are tannins, flavonoids and saponins.

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“…Berdasarkan hasil yang diperoleh menunjukkan bahwa ekstrak metanol daun suji dapat menghambat pertumbuhan bakteri S.sobrinus hingga konsentrasi minimum dengan kekuatan antibakteri sangat kuat hal ini dikarenakan senyawa metabolit berupa triterpenoid, steroid dan fenolik yang terkandung pada daun suji dapat bekerja dalam menghambat pertumbuhan bakteri S.sobrinus. Mekanisme kerja steroid dalam menghambat mikroba adalah dengan merusak membrane plasma sel mikroba, sehingga mneyebabkan bocornya sitoplasma keluar sel yang selanjutnya menyebabkan kematian sel [13]. Mekanisme senyawa triterpenoid sebagai senyawa antibakteri yaitu menurunkan permeabilitas membran sel bakteri yang disebabkan oleh komponen triterpenoid yang akan bereaksi dengan porin yaitu protein transmembran pada membran luar dinding sel bakteri dan membentuk ikatan polimer yang kuat sehingga porin akan rusak dan menurunkan permeabilitas sel bakteri sebagai pintu keluar masuk suatu senyawa [14].…”

Section: Uji Fitokimiaunclassified

Analisis Fitokimia Dan Uji Aktivitas Antibakteri Ekstrak Metanol Daun Suji (Pleomle Angusitolia N.E Brown)

Kurnia,

Ruga,

Saleh

2022

J. Kim. Mul

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Phytochemical and antibacterial activity assay of methanol extract from Suji leaves (Pleomele angustifolia) were carried out. The aims of this study are to determine secondary metabolites and antibacterial activity of the methanol extract against Streptococcus sobrinus KCCM 11898 and Streptococcus mutans ATCC 25175 by using agar well diffusion. The results showed that methanol extract of suji leaves contain phenolic, triterpenoid and steroid constituents. With 2%, the methanol extract displayed antibacterial activity against Streptococcus sobrinus and Streptococcus mutans with diameter inhibition zones of 19.0 and 10.3 mm, respectively.

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Manfaat Sirih Merah (Piper crocatum)sebagai Agen Anti Bakterial terhadap Bakteri Gram Positif dan Bakteri Gram Negatif

Cited by 14 publications

References 0 publications

Uji Aktivitas Antibakteri Ekstrak Etanol Daun Ungu (Graptophyllum pictum (L) Griff) terhadap Pertumbuhan Streptococcus sanguinis

Uji Aktivitas Antibakteri Ekstrak Etanol Daun Ungu (Graptophyllum pictum (L) Griff) terhadap Pertumbuhan Streptococcus sanguinis

Review Artikel : Aktivitas Antibakteri Daun Mangkokan (Nothopanax scutellarium)

Analisis Fitokimia Dan Uji Aktivitas Antibakteri Ekstrak Metanol Daun Suji (Pleomle Angusitolia N.E Brown)

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