Mandibular metastasis in a patient with pulmonary adenocarcinoma

Abstract

Metastatic tumour spread to the mandible is quite rare. We report a case of distant metastasis of pulmonary adenocarcinoma in the mandibular bone. The patient had pain in his left mandibular premolar-molar area caused by a mandibular metastasis from a previously undiagnosed pulmonary adenocarcinoma.

Metastasis of lung adenocarcinoma to the mandible: Report of a case

“…The clinical presentation of mandibular metastasis mimics common conditions, such as toothache, temporomandibular joint pain, osteomyelitis, trigeminal neuralgia, odontogenic infection, cysts, pyogenic granuloma, benign tumors, and primary malignancy. [ 11 ] In most of the patients who present with oral metastasis, the primary focus has generally been well diagnosed and treated. However, in very small number of patients the oral metastasis represents the initial finding, which ultimately leads to the detection of a hidden malignant lesion.…”

Unusual Presentation of an Adenocarcinoma of the Lung Metastasizing to the Mandible, Including Molecular Analysis and a Review of the Literature

“…Metastatic tumors in the jaw bone are uncommon; however; in the jaw, the most common location for a bone metastasis is the mandible, with the great majority of cases in the molarpremolar region [1,2,6,8,9,32], as was presented in the current case report.…”

Mandibular metastasis as the first clinical indication of occult lung adenocarcinoma with multiple metastases

“…[ 8 ] The pathogenesis of the mandibular metastasis is not fully understood; however, it is believed that the main mechanism of metastasis to the oral region is hematogenous associated with Batson venous plexus. [ 9 ] The most common metastatic site in the craniofacial region is the mandibular molar and premolar region because abrupt angulation of the vessel in this region causes slowing of the bloodstream, and it helps malignant cells deposit there. [ 9 ]…”

“…[ 9 ] The most common metastatic site in the craniofacial region is the mandibular molar and premolar region because abrupt angulation of the vessel in this region causes slowing of the bloodstream, and it helps malignant cells deposit there. [ 9 ]…”